CAS 1169562-71-3

8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride (1:?)

Description:

8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride is a chemical compound characterized by its complex structure, which includes a benzofuro-pyrimidine core and a pyrrolidine moiety. This compound is typically classified as a heterocyclic organic compound due to the presence of multiple ring structures containing nitrogen and oxygen atoms. The "8-chloro" designation indicates the presence of a chlorine atom at the 8th position of the benzofuro ring, which can influence its biological activity and solubility. The hydrochloride form suggests that the compound is a salt, enhancing its stability and solubility in aqueous solutions, which is often beneficial for pharmaceutical applications. This compound may exhibit various pharmacological properties, potentially acting as a modulator of specific biological pathways. Its specific interactions and efficacy would depend on its molecular structure and the presence of functional groups, making it a subject of interest in medicinal chemistry and drug development.

Formula: C₁₄H₁₂ClN₃O₂.x(HCl)

Synonyms:

• BMS-863233 HCl

(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one xhydrochloride

CAS: 1169562-71-3

(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one xhydrochloride

Purity: 98%

Molecular weight: 326.18g/mol

Ref: 54-OR1073872

XL413

Controlled Product

CAS: 1169562-71-3

Stability Hygroscopic
Applications XL413 is a potent and selective cell division cycle 7 homolog (CDC7) kinase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koltun, E., et al.: Bioorg. Med. Chem. Lett., 22, 3727 (2012)

Formula: C₁₄H₁₃Cl₂N₃O₂

Color and Shape: Neat

Molecular weight: 326.18

Ref: TR-X746230

XL413 hydrochloride

CAS: 1169562-71-3

XL413 hydrochloride is a potent small-molecule inhibitor, which is a synthetic compound specifically designed to target protein kinases. It acts as a selective inhibitor of Cdc7 kinase, a serine/threonine kinase essential for the initiation of DNA replication. This kinase is involved in the phosphorylation of MCM2 and the activation of the pre-replicative complex, a critical step in the S-phase of the cell cycle. By inhibiting Cdc7, XL413 hydrochloride effectively halts cell cycle progression, thereby impacting cellular proliferation.

Formula: C₁₄H₁₃Cl₂N₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 326.18 g/mol

Ref: 3D-UWB56271

XL413 xHCl

CAS: 1169562-71-3

BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215

Formula: C₁₄H₁₂ClN₃O₂·xHCl

Purity: 99.37% - 99.67%

Color and Shape: Solid

Molecular weight: 326.18

Ref: TM-T71339