CAS 117-89-5

trifluoperazine

Description:

Trifluoperazine is a phenothiazine derivative primarily used as an antipsychotic medication. It is characterized by its ability to block dopamine receptors in the brain, which helps in managing symptoms of schizophrenia and other psychotic disorders. The chemical formula of trifluoperazine is C20H22F3N3S, indicating the presence of three fluorine atoms, which contribute to its pharmacological properties. This compound is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. Trifluoperazine exhibits a moderate to high lipophilicity, allowing it to cross the blood-brain barrier effectively. It is also known for its sedative effects, which can be beneficial in treating agitation associated with psychotic episodes. However, like many antipsychotics, it may cause side effects, including extrapyramidal symptoms and sedation. Its use requires careful monitoring, especially in long-term treatment scenarios. Overall, trifluoperazine is a significant agent in psychiatric medicine, with a well-established profile in managing severe mental health conditions.

Formula: C₂₁H₂₄F₃N₃S

InChI: InChI=1/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H

InChI key: InChIKey=ZEWQUBUPAILYHI-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3

Synonyms:

• 10-(3-(4-Methylpiperazin-1-Yl)Propyl)-2-Trifluoromethylphenothiazine
• 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
• 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-trifluoromethylphenothiazine
• 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
• 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
• 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
• 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
• 2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine
• Flurazine
• Nsc 17474
• Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
• Rp 7623
• TFP
• Trifluoperazin
• Trifluoperazina
• Trifluoromethylperazine
• Trifluoroperazine
• Trifluperazine
• Triflurin
• Triperazine
• Trifluoperazine
• Triftazine
• Triphtazine
• Fluoperazine
• 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine
• trifluoromethyl-10-(3’-(1-methyl-4-piperazinyl)propyl)phenothiazine
• 10-(gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiozine
• 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazin
• Triphtazin
• 10-(gamma-(n’-methylpiperazino)propyl)-2-trifluoromethylphenothiazine
• Stellazine
• Trifluoperazine (base and/or unspecified salts)
• Trifluroperizine
• Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
• Terfluzine
• Jatroneural
• 10-(gamma-(n’-methylpiperazino)propyl)-2-trifluoromethylphenothiozine
• modalina
• Triphthazine
• rp7623
• Triftazin

Trifluoperazine Dihydrochloride

CAS: 117-89-5, 440-17-5, 605-75-4

Formula: C₂₁H₂₄F₃N₃S·2HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 480.42

Ref: 3B-T2849

10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine

CAS: 117-89-5

Formula: C₂₁H₂₄F₃N₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 407.4956

Ref: IN-DA000DJ9

Trifluoperazine

CAS: 117-89-5

Trifluoperazine

Purity: ≥98%

Molecular weight: 407.5g/mol

Ref: 54-BUP04613

Trifluoperazine

CAS: 117-89-5

Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.

Formula: C₂₁H₂₄F₃N₃S

Purity: 98.3% - 99.46%

Color and Shape: White To Yellowish Crystalline Powder

Molecular weight: 407.5

Ref: TM-T8389