CAS 117-89-5: trifluoperazine

Description: Trifluoperazine is a phenothiazine derivative primarily used as an antipsychotic medication. It is characterized by its ability to block dopamine receptors in the brain, which helps in managing symptoms of schizophrenia and other psychotic disorders. The chemical formula of trifluoperazine is C20H22F3N3S, indicating the presence of three fluorine atoms, which contribute to its pharmacological properties. This compound is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. Trifluoperazine exhibits a moderate to high lipophilicity, allowing it to cross the blood-brain barrier effectively. It is also known for its sedative effects, which can be beneficial in treating agitation associated with psychotic episodes. However, like many antipsychotics, it may cause side effects, including extrapyramidal symptoms and sedation. Its use requires careful monitoring, especially in long-term treatment scenarios. Overall, trifluoperazine is a significant agent in psychiatric medicine, with a well-established profile in managing severe mental health conditions.

Formula: C₂₁H₂₄F₃N₃S

InChI: InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3

InChI key: InChIKey=ZEWQUBUPAILYHI-UHFFFAOYSA-N

SMILES: FC(F)(F)C1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN4CCN(C)CC4

Synonyms:

• 10-(3-(4-Methylpiperazin-1-Yl)Propyl)-2-Trifluoromethylphenothiazine
• 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
• 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-trifluoromethylphenothiazine
• 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
• 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
• 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
• 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
• 2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine
• Flurazine
• Nsc 17474
• Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
• Rp 7623
• TFP
• Trifluoperazin
• Trifluoperazina
• Trifluoromethylperazine
• Trifluoroperazine
• Trifluperazine
• Triflurin
• Triperazine
• Trifluoperazine

Trifluoperazine Dihydrochloride

CAS: 117-89-5440-17-5 605-75-4

• Formula: C₂₁H₂₄F₃N₃S·2HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 480.42

10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-

CAS: 117-89-5

• Formula: C₂₁H₂₄F₃N₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 407.4956

Trifluoperazine

CAS: 117-89-5

• Purity: 99%
• Molecular weight: 407.5g/mol

Trifluoperazine

CAS: 117-89-5

Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.

• Formula: C₂₁H₂₄F₃N₃S
• Purity: 98.3% - 99.46%
• Color and Shape: White To Yellowish Crystalline Powder
• Molecular weight: 407.5

Trifluoperazine

CAS: 117-89-5

Trifluoperazine is a p-glycoprotein inhibitor that has been shown to inhibit the cytosolic Ca2+ influx …

• Formula: C₂₁H₂₄F₃N₃S
• Purity: Min. 95%
• Molecular weight: 407.5 g/mol