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CAS 117027-34-6

:

interleukin 1B antagonist

Description:
Interleukin 1B antagonist, with the CAS number 117027-34-6, is a synthetic peptide that functions as an inhibitor of interleukin-1 beta (IL-1β), a pro-inflammatory cytokine involved in various immune responses. This antagonist is primarily utilized in research and therapeutic applications to modulate inflammatory processes, particularly in conditions such as rheumatoid arthritis and other inflammatory diseases. The compound works by binding to the IL-1 receptor, thereby preventing IL-1β from exerting its biological effects, which include the activation of inflammatory pathways and the promotion of fever. Characteristically, interleukin 1B antagonist is known for its specificity and potency in blocking IL-1β activity, making it a valuable tool in both experimental and clinical settings. Its pharmacological profile includes a favorable safety margin, although potential side effects may arise depending on the context of use. Overall, this antagonist represents a significant advancement in the management of inflammatory conditions, highlighting the importance of cytokine modulation in therapeutic strategies.
Formula:C15H28N4O5
InChI:InChI=1/C15H28N4O5/c1-9(20)12(15(23)24)18-13(21)11-6-4-8-19(11)14(22)10(17)5-2-3-7-16/h9-12,20H,2-8,16-17H2,1H3,(H,18,21)(H,23,24)/t9-,10+,11-,12+/m1/s1
Synonyms:
  • (D-Pro194)-IL-1.beta. (193-195) (human)
  • H-Lys-D-Pro-Thr-OH
  • L-lysyl-D-prolyl-L-threonine
  • (D-PRO194)-IL-1B (193-195) (HUMAN)
  • (D-PRO194)-INTERLEUKIN-1BETA (193-195) (HUMAN)
  • (D-PRO194)-IL-1BETA (193-195) (HUMAN)
  • (D-PRO194)-INTERLEUKIN-1B (193-195) (HUMAN)
  • L-LYS-D-PRO-L-THR
  • L-Threonine, L-lysyl-D-prolyl-
  • (D-Pro194)-Interleukin-1β (193-195) (human)
  • See more synonyms
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Found 3 products.
  • Lys-D-Pro-Thr
    Indagoo
    + Info

    Lys-D-Pro-Thr

    CAS:
    Formula:C15H28N4O5
    Purity:99%
    Molecular weight:344.4066

    Ref: IN-DA000DL9

    5mg
    554.00€
    10mg
    To inquire
    25mg
    To inquire
  • Interleukin 1β
    Targetmol
    + Info

    Interleukin 1β

    CAS:
    Interleukin 1beta is a bioactive chemical.
    Formula:C15H28N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:344.41

    Ref: TM-T21048

  • (D-Pro194)-IL-1beta (193-195) (human)
    Biosynth
    + Info

    (D-Pro194)-IL-1beta (193-195) (human)

    CAS:
    <p>IL-1beta is a pro-inflammatory cytokine that belongs to the group of interleukins. It is synthesized as a preproprotein which undergoes proteolytic processing to produce a mature 34 kDa protein with an N-terminal lys-pro sequence. IL-1beta has been shown to induce allergic reactions in animals and humans, constrictions in airways, and antigen presentation by antigen presenting cells, such as macrophages and dendritic cells. This cytokine also has costimulatory effects on immune responses and has been shown to be involved in autoimmune diseases and inflammatory diseases. The IL-1beta gene contains a hydroxyl group at the COOH terminus that allows for the formation of an aspirin binding site.</p>
    Formula:C15H28N4O5
    Purity:Min. 95%
    Molecular weight:344.41 g/mol

    Ref: 3D-FP110010

    25mg
    863.00€
    50mg
    1,331.00€
    100mg
    2,254.00€