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CAS 117088-31-0

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FMOC-THR(TBU)-OPFP

Description:
FMOC-THR(TBU)-OPFP, with the CAS number 117088-31-0, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of threonine, an amino acid, and features a fluorenylmethyloxycarbonyl (FMOC) protecting group, which is widely utilized to protect amino groups during peptide synthesis. The presence of the tert-butyl (TBU) group further enhances the stability and solubility of the compound, making it suitable for various synthetic applications. The OPFP moiety indicates the presence of a phosphonium salt, which can facilitate coupling reactions in peptide synthesis. This compound is typically characterized by its solid state, stability under standard laboratory conditions, and its ability to undergo deprotection under specific conditions to yield the free amino acid or peptide. Its utility in solid-phase peptide synthesis and other organic synthesis applications makes it a valuable reagent in the field of biochemistry and medicinal chemistry. Proper handling and storage conditions are essential to maintain its integrity and reactivity.
Formula:C29H26F5NO5
InChI:InChI=1/C29H26F5NO5/c1-14(40-29(2,3)4)25(27(36)39-26-23(33)21(31)20(30)22(32)24(26)34)35-28(37)38-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19,25H,13H2,1-4H3,(H,35,37)/t14-,25+/m1/s1
Synonyms:
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-O-T-Butyl-L-Threonine Pentafluorphenol Ester
  • Fmoc-Threonine(Tbu)-Opfp
  • Fmoc-O-Tert-Butyl-L-Threonine Pentafluorophenyl Ester
  • Fmoc-O-T-Butyl-L-Threonine Pentafluorophenyl Ester
  • Fmoc-L-Thr(Tbu)-Opfp
  • Fmoc-O-Tert-Butyl-L-Threonine Penta-Fluorophenyl Ester, Tech 90+%
  • pentafluorophenyl O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threoninate
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