CAS 117106-20-4: O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine
Description:O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine, commonly referred to by its CAS number 117106-20-4, is a synthetic compound primarily used in peptide synthesis and as a protecting group in organic chemistry. This molecule features a threonine amino acid backbone, which is modified with a tert-butyl group (1,1-dimethylethyl) and a fluorenylmethoxycarbonyl (Fmoc) protecting group. The Fmoc group is widely utilized for its stability under basic conditions and ease of removal under acidic conditions, making it advantageous in solid-phase peptide synthesis. The presence of the methyl group on the nitrogen atom contributes to the steric hindrance, influencing the compound's reactivity and solubility. This compound is typically characterized by its solid-state properties, including melting point and solubility in organic solvents. Its unique structure allows for specific interactions in biochemical applications, particularly in the synthesis of peptides and proteins, facilitating the study of biological processes and the development of pharmaceuticals.
Formula:C24H29NO5
InChI:InChI=1S/C24H29NO5/c1-15(30-24(2,3)4)21(22(26)27)25(5)23(28)29-14-20-18-12-8-6-10-16(18)17-11-7-9-13-19(17)20/h6-13,15,20-21H,14H2,1-5H3,(H,26,27)/t15-,21+/m1/s1
InChI key:InChIKey=VIUVLZHFMIFLHU-VFNWGFHPSA-N
SMILES:O=C(O)C(N(C(=O)OCC1C=2C=CC=CC2C=3C=CC=CC31)C)C(OC(C)(C)C)C
- Synonyms:
- <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- N-Fmoc-N-Methyl-O-Tert-Butyl-L-Threonine
- O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-threonine
- O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine
- L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine