CAS 117136-35-3

1-[(2R,3S,4S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

Description:

The chemical substance known as 1-[(2R,3S,4S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, with the CAS number 117136-35-3, is a complex organic compound characterized by its unique structural features. It contains a pyrimidine ring, which is a six-membered heterocyclic compound with nitrogen atoms, and a tetrahydrofuran moiety, a five-membered cyclic ether. The presence of various functional groups, including a tert-butyl(dimethyl)silyl ether and a trityloxymethyl group, contributes to its chemical reactivity and solubility properties. This compound is likely to exhibit specific stereochemistry due to the chiral centers present in the tetrahydrofuran ring, influencing its biological activity and interactions. Its synthesis and manipulation may require careful consideration of its stability and reactivity under different conditions, making it of interest in medicinal chemistry and organic synthesis. Overall, this compound exemplifies the complexity and diversity of organic molecules used in various chemical applications.

Formula: C₃₄H₄₀N₂O₆Si

InChI: InChI=1/C34H40N2O6Si/c1-33(2,3)43(4,5)42-30-29(38)27(41-31(30)36-22-21-28(37)35-32(36)39)23-40-34(24-15-9-6-10-16-24,25-17-11-7-12-18-25)26-19-13-8-14-20-26/h6-22,27,29-31,38H,23H2,1-5H3,(H,35,37,39)/t27-,29+,30+,31-/m1/s1

Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-(triphenylmethyl)-

CAS: 117136-35-3

Formula: C₃₄H₄₀N₂O₆Si

Color and Shape: Solid

Molecular weight: 600.7767

Ref: IN-DA000DSY

2’-O-(tert-Butyldimethylsilyl)-5’-O-trityluridine

CAS: 117136-35-3

Ref: 7W-GN7439

2’-O-(tert-Butyldimethylsilyl)-5’-O-trityluridine

Controlled Product

CAS: 117136-35-3

Applications A protected potential anti-cancer and anti-viral agent.
References Lin, T-S., et al.: J. Med. Chem., 34, 693 (1991),

Formula: C₃₄H₄₀N₂O₆Si

Color and Shape: Neat

Molecular weight: 600.78

Ref: TR-B691710

2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine

CAS: 117136-35-3

2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine is a synthetic nucleoside that is used in the synthesis of DNA, RNA and other nucleosides. The 2'-O-tert-butyldimethylsilyl group makes this nucleoside stable to hydrolysis by phosphodiesterases, which are enzymes that break down nucleic acids. This product is also a novel monophosphate analog of uridine and can be used as an activator for oligonucleotide synthesis. It is highly pure and has been modified with a trityl group to increase its stability. The CAS number for this product is 117136-35-3.

Formula: C₃₄H₄₀N₂O₆Si

Purity: Min. 95%

Molecular weight: 600.78 g/mol

Ref: 3D-NB16515