CAS 117141-39-6

tert-butyloxycarbonyl-leucyl-glycyl-arginine-4-trifluoromethylcoumarin-7-amide

Description:

Tert-butyloxycarbonyl-leucyl-glycyl-arginine-4-trifluoromethylcoumarin-7-amide, commonly referred to as a peptide derivative, is characterized by its complex structure that includes a tert-butyloxycarbonyl (Boc) protecting group, amino acid residues (leucine, glycine, and arginine), and a coumarin moiety. The presence of the Boc group indicates that this compound is likely used in peptide synthesis, providing protection for the amine group during chemical reactions. The incorporation of the trifluoromethylcoumarin component suggests that this compound may exhibit fluorescence properties, making it useful in biochemical assays or as a fluorescent probe. Additionally, the amino acid sequence contributes to its potential biological activity, possibly influencing interactions with biological targets or enzymes. The compound's stability, solubility, and reactivity can be influenced by its functional groups and overall molecular structure, which are critical for its application in research and development, particularly in the fields of medicinal chemistry and biochemistry.

Formula: C₂₉H₄₀F₃N₇O₇

InChI: InChI=1/C29H40F3N7O7/c1-15(2)11-20(38-27(44)46-28(3,4)5)24(42)36-14-22(40)39-25(43)19(7-6-10-35-26(33)34)37-16-8-9-17-18(29(30,31)32)13-23(41)45-21(17)12-16/h8-9,12-13,15,19-20,37H,6-7,10-11,14H2,1-5H3,(H,36,42)(H,38,44)(H4,33,34,35)(H,39,40,43)/t19-,20-/m0/s1

SMILES: CC(C)C[C@@H](C(=NCC(=NC(=O)[C@H](CCCNC(=N)N)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F)O)O)N=C(O)OC(C)(C)C

Synonyms:

• Boc-leu-gly-arg-afc
• Lga-afc
• N-((1,1-Dimethylethoxy)carbonyl)-L-leucylglycyl-N-(2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl)-L-argininamide
• L-Argininamide, N-((1,1-dimethylethoxy)carbonyl)-L-leucylglycyl-N-(2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl)-
• N-(tert-butoxycarbonyl)-L-leucyl-N-[(2S)-5-[(diaminomethylidene)amino]-2-{[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]amino}pentanoyl]glycinamide
• tert-Butyloxycarbonyl-leucyl-glycyl-arginine-4-trifluoromethylcoumarin-7-amide