CAS 1172-18-5

Flurazepam hydrochloride

Description:

Flurazepam hydrochloride is a benzodiazepine derivative primarily used as a sedative and hypnotic for the treatment of insomnia. It is characterized by its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased sedation and anxiolytic effects. The substance appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its administration in various pharmaceutical formulations. Flurazepam has a relatively long half-life compared to other benzodiazepines, which contributes to its prolonged sedative effects. Common side effects may include drowsiness, dizziness, and potential dependence with prolonged use. Due to its pharmacological properties, it is classified as a controlled substance in many jurisdictions, necessitating careful prescription and monitoring by healthcare professionals. As with other benzodiazepines, caution is advised in patients with a history of substance abuse or certain medical conditions.

Formula: C₂₁H₂₃ClFN₃O·2ClH

InChI: InChI=1S/C21H23ClFN3O.2ClH/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23;;/h5-10,13H,3-4,11-12,14H2,1-2H3;2*1H

InChI key: InChIKey=ZIIJJOPLRSCQNX-UHFFFAOYSA-N

SMILES: C(CN(CC)CC)N1C=2C(C(=NCC1=O)C3=C(F)C=CC=C3)=CC(Cl)=CC2.Cl

Synonyms:

• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, dihydrochloride
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, hydrochloride (1:2)
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-1,3-dihydro-, dihydrochloride
• 7-Chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one dihydrochloride
• 7-Chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one dihydrochloride
• 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one dihydrochloride
• Benozil
• Dalmadorm
• Dalmane
• Dalmate
• Dormodor
• Felson
• Flurazepam Dihydrochloride
• Flurazepam Hydrochloride
• Flurazepam di hcl
• Id 480
• Insumin
• Lunipax
• NSC 78559
• Ro 5-6901

Flurazepam Dihydrochloride

Controlled Product

CAS: 1172-18-5

Color and Shape: Neat

Ref: 86-MM3604.00

Flurazepam Dihydrochloride (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 1172-18-5

Formula: C₂₁H₂₃ClFN₃O·2ClH

Color and Shape: Single Solution

Molecular weight: 460.80

Ref: TR-KIT4745

Flurazepam dihydrochloride

Controlled Product

CAS: 1172-18-5

Antagonist of GABA(A) receptor

Formula: C₂₁H₂₃ClFN₃O·2ClH

Purity: Min. 95%

Molecular weight: 460.8 g/mol

Ref: 3D-FF35405

Flurazepam Hydrochloride CIV

Controlled Product

CAS: 1172-18-5

Alprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) only

Formula: C₂₁H₂₃ClFN₃O·2ClH

Color and Shape: Off-White Light Yellow Powder

Molecular weight: 459.10472

Ref: 45-1285002

Flurazepam Dihydrochloride

Controlled Product

CAS: 1172-18-5

Applications Flurazepam Dihydrochloride is used as an sedative, hypnotic. This is a controlled substance (depressant).
References Sternbach, L.H., et al.: J. Med. Chem., 8, 815 (1965); Schwartz, et al.: J. Med. Chem., 11, 770, (1968); Armagnac, et al.: Therapie, 26, 439 (1971); Ganjali, M., et al.: Curr. Pharm. Anal., 5, 28 (2009);

Formula: C₂₁H₂₃ClFN₃O·2ClH

Color and Shape: Light Orange Colour To Yellow

Molecular weight: 460.80

Ref: TR-F500800