CAS 1173020-43-3

Fluoxetine-D5 hydrochloride

Description:

Fluoxetine-D5 hydrochloride is a deuterated form of fluoxetine, a selective serotonin reuptake inhibitor (SSRI) commonly used in the treatment of depression, anxiety disorders, and certain other psychiatric conditions. The "D5" designation indicates that five hydrogen atoms in the molecule have been replaced with deuterium, a stable isotope of hydrogen, which can be useful in pharmacokinetic studies and metabolic research. This modification can enhance the stability and tracking of the compound in biological systems. Fluoxetine-D5 hydrochloride typically appears as a white to off-white solid and is soluble in water and organic solvents, making it suitable for various analytical applications. Its molecular structure retains the core characteristics of fluoxetine, allowing it to interact with serotonin transporters in a similar manner, while the deuteration provides a unique tool for studying drug metabolism and dynamics without altering the pharmacological properties significantly. As with all chemical substances, proper handling and safety protocols should be observed when working with this compound.

Formula: C₁₇H₁₄ClD₅F₃NO

Synonyms:

• Fluoxetine hydrochloride salt
• Fluoxetine-d5 hydrochloride (phenyl-d5)
• N-methyl-3-(2,3,4,5,6-pentadeuteriophenyl)-3-[4-(trifluoromethyl)phenoxy]propan-1-amine:hydrochloride
• N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-(phenyl-d5)-propylamine hydrochloride

Fluoxetine-d5 HCl

CAS: 1173020-43-3

Formula: C₁₇H₁₃D₅F₃NO·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 314.36 36.46

Ref: 4Z-F-072

(+/-)-Fluoxetine-d5 HCl(phenyl-d5)

CAS: 1173020-43-3

Purity: 99 atom % D

Color and Shape: White Solid

Molecular weight: 350.82

Ref: 3U-D5749

Fluoxetine-d5 Hydrochloride

Controlled Product

CAS: 1173020-43-3

Applications A labelled selective serotonin reuptake inhibitor (SSRI). Used as an antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wong, D.T., et al.: Life Sci., 15, 471 (1974), Goldstein, D.J., et al.: Br. J. Psychiat., 166, 660 (1995), Ni, Y.G., et al.: Proc. Nat. Acad. Sci. USA, 94, 2036 (1997)

Formula: C₁₇₂H₅H₁₃F₃NO·ClH

Color and Shape: Off White Solid

Molecular weight: 350.82

Ref: TR-F597102

Fluoxetine-d5 hydrochloride

Controlled Product

CAS: 1173020-43-3

Fluoxetine-d5 hydrochloride is a fluorinated form of fluoxetine, which is a nonsteroidal anti-inflammatory drug. Fluoxetine-d5 hydrochloride has been shown to be an ATP binding cassette transporter inhibitor, meaning that it blocks the uptake of adenosine triphosphate (ATP) in cells. This inhibition may be due to its ability to bind to muscle tissue and act as a matrix effect enhancer, which leads to increased ATP production in muscle cells. Fluoxetine-d5 hydrochloride has also been shown to inhibit acetaminophen metabolism by blocking the activity of cytochrome P450 enzymes.

Formula: C₁₇H₁₃D₅F₃NO•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 350.82 g/mol

Ref: 3D-YWB02043