CAS 1173706-35-8

N-Octylnortadalafil

Description:

N-Octylnortadalafil is a synthetic compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which are primarily used in the treatment of erectile dysfunction. This substance is a derivative of tadalafil, a well-known medication that enhances blood flow by inhibiting the breakdown of cyclic guanosine monophosphate (cGMP). N-Octylnortadalafil features a long alkyl chain, which may influence its pharmacokinetic properties, such as solubility and absorption. The compound is characterized by its ability to selectively target the PDE5 enzyme, leading to vasodilation and increased blood flow to specific areas of the body. Its chemical structure includes functional groups that contribute to its biological activity and stability. As with other PDE5 inhibitors, potential side effects may include headaches, flushing, and gastrointestinal disturbances. Research into N-Octylnortadalafil may focus on its efficacy, safety profile, and potential applications in various therapeutic areas beyond erectile dysfunction.

Formula: C₂₉H₃₃N₃O₄

InChI: InChI=1S/C29H33N3O4/c1-2-3-4-5-6-9-14-31-17-26(33)32-23(29(31)34)16-21-20-10-7-8-11-22(20)30-27(21)28(32)19-12-13-24-25(15-19)36-18-35-24/h7-8,10-13,15,23,28,30H,2-6,9,14,16-18H2,1H3/t23-,28-/m1/s1

InChI key: InChIKey=JIMWYJMUPCVOFA-QDPGVEIFSA-N

SMILES: O=C1N2[C@@H](C3=C(C=4C(N3)=CC=CC4)C[C@@]2(C(=O)N(CCCCCCCC)C1)[H])C=5C=C6C(=CC5)OCO6

Synonyms:

• (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-octylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
• N-Octyltadalafil
• N-Octylnortadalafil
• Pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-octyl-, (6R,12aR)-
• N-Octyl Nortadalafil
• (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-octylpyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
• Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-octyl-, (6R,12aR)-

N-Octyl-Nortadalafil

CAS: 1173706-35-8

Formula: C₂₉H₃₃N₃O₄

Color and Shape: White To Off-White Solid

Molecular weight: 487.60

Ref: 4Z-T-105

N-Octyl Nortadalafil

Controlled Product

CAS: 1173706-35-8

Applications Tadalafil (T004500) analog which is a phosphodiesterase 5 inhibitor.
References Jiru, M., et al.: J. Pharm. Biomed. Anal., 164, 713-724 (2019)

Formula: C₂₉H₃₃N₃O₄

Color and Shape: White To Off-White

Molecular weight: 487.59

Ref: TR-O241350

N-Octyl-Nortadalafil

CAS: 1173706-35-8

Formula: C₂₉H₃₃N₃O₄

Molecular weight: 487.6

Ref: ST-EA-CP-T31083