CAS 1174018-99-5

Relebactam

Description:

Relebactam is a synthetic beta-lactamase inhibitor that is primarily used in combination with other antibiotics to enhance their efficacy against resistant bacterial strains. It is particularly effective against certain Gram-negative bacteria that produce beta-lactamase enzymes, which can inactivate many beta-lactam antibiotics. Relebactam is characterized by its ability to inhibit the activity of class A and some class C beta-lactamases, thereby restoring the activity of co-administered beta-lactam antibiotics like meropenem. The compound has a molecular formula that reflects its complex structure, which includes a beta-lactam ring, a key feature that contributes to its mechanism of action. Relebactam is typically administered intravenously and is being investigated for its potential in treating serious infections caused by multidrug-resistant organisms. Its development is part of a broader effort to combat antibiotic resistance, a significant public health challenge. As with many pharmaceuticals, the safety and efficacy of Relebactam are evaluated through clinical trials before it is approved for widespread clinical use.

Formula: C₁₂H₂₀N₄O₆S

InChI: InChI=1S/C12H20N4O6S/c17-11(14-8-3-5-13-6-4-8)10-2-1-9-7-15(10)12(18)16(9)22-23(19,20)21/h8-10,13H,1-7H2,(H,14,17)(H,19,20,21)/t9-,10+/m1/s1

InChI key: InChIKey=SMOBCLHAZXOKDQ-ZJUUUORDSA-N

SMILES: C(NC1CCNCC1)(=O)[C@H]2[N@@]3C(=O)N(OS(=O)(=O)O)[C@@](C3)(CC2)[H]

Synonyms:

• Relebactam
• (2S,5R)-7-oxo-2-(piperidin-1-ium-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
• (2S,5R)-sulfuric acid mono{[(4-aminopiperidin-4-yl)carbonyl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl}ester
• Sulfuric acid Mono-[7-oxo-2-(piperidin-4-ylcarbaMoyl)-1,6-diaza-bicyclo[3.2.1]oct-6-yl] ester
• Sulfuric acid mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester
• Sulfuric acid, mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester
• MK 7655
• MK-7655;MK 7655;MK7655
• MK7655
• CS-2637
• MK-7655(Relebactam)

Sulfuric acid mono-[7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diaza-bicyclo[3.2.1]oct-6-yl] ester

CAS: 1174018-99-5

Formula: C₁₂H₂₀N₄O₆S

Purity: 97%

Color and Shape: Solid

Molecular weight: 348.3754

Ref: IN-DA008TPH

Relebactam

CAS: 1174018-99-5

Relebactam

Purity: ≥98%

Molecular weight: 348.38g/mol

Ref: 54-BUP05334

Relebactam

CAS: 1174018-99-5

Formula: C₁₂H₂₀N₄O₆S

Molecular weight: 348.37

Ref: 4Z-R-138001

Relebactam

CAS: 1174018-99-5

Formula: C₁₂H₂₀N₄O₆S

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to off-white powder or crystals

Molecular weight: 348.11

Ref: 7W-GP5674

(1R,2S,5R)-7-Oxo-2-(Piperidin-4-Ylcarbamoyl)-1,6-Diazabicyclo[3.2.1]Octan-6-Yl Hydrogen Sulfate

CAS: 1174018-99-5

(1R,2S,5R)-7-Oxo-2-(Piperidin-4-Ylcarbamoyl)-1,6-Diazabicyclo[3.2.1]Octan-6-Yl Hydrogen Sulfate

Purity: 98%

Molecular weight: 348.38g/mol

Ref: 54-OR1023222

Relebactam-d4

CAS: 1174018-99-5

Formula: C₁₂H₁₆D₄N₄O₆S

Molecular weight: 352.40

Ref: 4Z-R-138002

Relebactam

CAS: 1174018-99-5

Relebactam (MK-7655) is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases.

Formula: C₁₂H₂₀N₄O₆S

Purity: 97.38% - >99.99%

Color and Shape: Solid

Molecular weight: 348.38

Ref: TM-T4017

Relebactam

Controlled Product

CAS: 1174018-99-5

Formula: C₁₂H₂₀N₄O₆S

Color and Shape: Neat

Molecular weight: 348.38

Ref: TR-R143403

Relebactam

CAS: 1174018-99-5

Inhibitor of beta-lactamase enzymes

Formula: C₁₂H₂₀N₄O₆S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 348.38 g/mol

Ref: 3D-BR163749