
CAS 1175002-03-5
:DMABA-d4 NHS ester
Description:
DMABA-d4 NHS ester, identified by its CAS number 1175002-03-5, is a chemical compound that features a deuterated form of DMABA (dimethylaminobenzylamine) linked to a N-hydroxysuccinimide (NHS) ester. This compound is characterized by its ability to facilitate the conjugation of biomolecules, such as proteins or peptides, due to the reactive NHS ester group, which readily reacts with amines to form stable amide bonds. The deuterated nature of DMABA-d4 allows for enhanced tracking and analysis in various applications, particularly in mass spectrometry and NMR spectroscopy, where deuterium can provide distinct signals. Additionally, the presence of the dimethylamino group contributes to its solubility in organic solvents and its potential utility in bioconjugation strategies. Overall, DMABA-d4 NHS ester is a valuable tool in chemical biology and biochemistry for the labeling and modification of biomolecules.
Formula:C13H10D4N2O4
Synonyms:- DMABA-d4 NHS ester
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DMABA-d4 NHS Ester
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Labelled DMABA NHS ester (D678400). DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 to study relative changes in PE lipid abundance before and after radical oxidation.<br>References Wester, H., et al.: Nucl. Med. Bio., 23, 365 (1996), Frees, D., et al.: Mol. Microbiol., 48, 1565 (2003), Michel, A., et al.: J. Bacteriol., 188, 5783 (2006), Voelker, T., et al.: Bioorg. Med. Chem., 17, 2047 (2009),<br></p>Formula:C13H10D4N2O4Color and Shape:NeatMolecular weight:266.29
