CAS 117525-25-4

9-(2,3-dideoxy-2-fluoro-betaD-threo-pentofuranosyl)hypoxanthine

Description:

9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)hypoxanthine, identified by its CAS number 117525-25-4, is a nucleoside analog that features a hypoxanthine base linked to a modified sugar moiety. This compound is characterized by the presence of a dideoxy sugar, specifically a 2-fluoro-beta-D-threo-pentofuranosyl group, which alters its biological properties compared to standard nucleosides. The fluorine substitution at the 2-position enhances its stability and may influence its interaction with nucleic acid targets. As a nucleoside analog, it has potential applications in antiviral and anticancer therapies, as it can interfere with nucleic acid synthesis. The structural modifications contribute to its unique pharmacological profile, making it a subject of interest in medicinal chemistry and drug development. Its solubility, stability, and bioavailability are critical factors that determine its efficacy in therapeutic applications. Overall, this compound exemplifies the ongoing efforts to design modified nucleosides for improved therapeutic outcomes.

Formula: C₁₀H₁₁FN₄O₃

InChI: InChI=1/C10H11FN4O3/c11-6-1-5(2-16)18-10(6)15-4-14-7-8(15)12-3-13-9(7)17/h3-6,10,16H,1-2H2,(H,12,13,17)/t5-,6-,10+/m0/s1

Synonyms:

• 2'-F-dd-Aral
• 6H-Purin-6-one, 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-1,9-dihydro-
• 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-3,9-dihydro-6H-purin-6-one
• 9-(2,3-Dideoxy-2-fluoro-betad-threo-pentofuranosyl)hypoxanthine