CAS 117591-20-5

CALPEPTIN

Description:

Calpeptin is a synthetic compound known for its role as a calpain inhibitor, which means it inhibits the activity of calpain enzymes involved in various cellular processes, including apoptosis and cell signaling. It is characterized by its ability to modulate proteolytic activity, making it of interest in research related to cancer, neurodegenerative diseases, and other conditions where calpain activity is implicated. Calpeptin is typically presented as a white to off-white solid and is soluble in organic solvents, but its solubility in water is limited. The compound has been studied for its potential therapeutic applications, particularly in the context of inhibiting tumor growth and protecting against cellular damage. Its mechanism of action involves binding to the active site of calpain, thereby preventing substrate cleavage. As with many chemical substances, safety and handling precautions are essential, as calpeptin may have specific toxicity profiles that require careful consideration in laboratory settings.

Formula: C₂₀H₃₀N₂O₄

InChI: InChI=1/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17?,18-/m0/s1

InChI key: InChIKey=PGGUOGKHUUUWAF-ROUUACIJSA-N

SMILES: [C@H](C(N[C@@H](CCCC)C=O)=O)(NC(OCC1=CC=CC=C1)=O)CC(C)C

Synonyms:

• Benzyloxycarbonyldipeptidyl Aldehyde
• Benzyloxycarbonylleucyl-Norleucinal
• Carbamic acid, N-[(1S)-1-[[[(1S)-1-formylpentyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester
• Carbamic acid, [(1S)-1-[[[(1S)-1-formylpentyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester
• Carbamic acid, [1-[[(1-formylpentyl)amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester, [S-(R*,R*)]-
• N-Benzyloxycarbonyl-L-Leucylnorleucinal
• N-Cbz-L-Leucyl-Norleucinal
• N-[N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl]-<smallcap>L</span>-norleucinal
• N~2~-[(benzyloxy)carbonyl]-N-(1-oxohexan-2-yl)-L-leucinamide
• N~2~-[(benzyloxy)carbonyl]-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide
• Z-Leu-Nle-Cho
• Z-Leu-Nle-Oh
• Z-Leu-Norleucinal
• Calpeptin
• N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinal
• CalpeptinN-Benzyloxycarbonyl-L-leucyl-norleucinal
• Calpeptin,95%
• N-[(1S)-1-[[(1S)-1-Formylpentyl]Carbamoyl]-3-Methyl-Butyl]Carbamic Acid Be
• CS-1747
• N-Benzyloxycarbonyl-L-leucylnorieucinal
• Z-LEU-NORLEUCINAL;N-BENZYLOXYCARBONYL-L-LEUCYL-NORLEUCINAL
• N-[(1S)-1-[[[(1S)-1-Formylpentyl]Amino]-Oxomethyl]-3-Methylbutyl]Carbamic Acid Phenylmethyl Ester
• Calpeptin - CAS 117591-20-5 - Calbiochem
• benzyl (S)-4-methyl-1-oxo-1-((S)-1-oxohexan-2-ylamino)pentan-2-ylcarbamate
• Phenylmethyl N-[(1S)-1-[[(1S)-1-Formylpentyl]Carbamoyl]-3-Methyl-Butyl]Carbamate

Calpeptin

CAS: 117591-20-5

Formula: C₂₀H₃₀N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 362.4632

Ref: IN-DA007QWY

Calpeptin

CAS: 117591-20-5

Calpeptin

Purity: ≥95%

Molecular weight: 362.46g/mol

Ref: 54-BUP05911

Calpeptin

CAS: 117591-20-5

Calpeptin is a potent, cell-permeable calpain inhibitor.

Formula: C₂₀H₃₀N₂O₄

Purity: 97.06% - 98.33%

Color and Shape: White To Off-White Powder

Molecular weight: 362.46

Ref: TM-T6432

Calpeptin

Controlled Product

CAS: 117591-20-5

Formula: C₂₀H₃₀N₂O₄

Color and Shape: Neat

Molecular weight: 362.463

Ref: TR-C148800