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CAS 1176-08-5

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phenyltoloxamine citrate

Description:
Phenyltoloxamine citrate is a chemical compound primarily recognized for its antihistaminic properties. It is a derivative of tolfenamic acid and is often used in the formulation of medications aimed at alleviating allergic symptoms. The substance acts as an antagonist to histamine H1 receptors, thereby reducing the effects of histamine in the body, which can include symptoms such as itching, sneezing, and runny nose. Phenyltoloxamine citrate is typically administered in oral form and is known for its relatively rapid onset of action. In terms of physical characteristics, it is usually presented as a white to off-white crystalline powder, which is soluble in water and exhibits stability under standard storage conditions. Its pharmacological profile includes sedative effects, which may limit its use in certain populations, particularly those requiring alertness. As with any medication, potential side effects and contraindications should be considered, and it is essential to consult healthcare professionals for appropriate usage.
Formula:C23H29NO8
InChI:InChI=1/C17H21NO.C6H8O7/c1-18(2)12-13-19-17-11-7-6-10-16(17)14-15-8-4-3-5-9-15;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-11H,12-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key:InChIKey=ZZYHCCDMBJTROG-UHFFFAOYSA-N
SMILES:C(C1=C(OCCN(C)C)C=CC=C1)C2=CC=CC=C2.C(CC(O)=O)(CC(O)=O)(C(O)=O)O
Synonyms:
  • 2-(2-Benzylphenoxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate
  • 2-(2-benzylphenoxy)-N,N-dimethylethanaminium 3,4-dicarboxy-3-hydroxybutanoate
  • Ethanamine, N,N-dimethyl-2-[2-(phenylmethyl)phenoxy]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
  • Ethylamine, N,N-dimethyl-2-[(α-phenyl-o-tolyl)oxy]-, citrate (1:1)
  • Kutrase
  • Mobigesic
  • NSC 148352
  • NSC 169860
  • Nih 10121
  • Phenoxadrine citrate
  • See more synonyms
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