CAS 1176-82-5

Fluocortolone Acetate

Description:

Fluocortolone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various skin conditions and inflammatory disorders. It is characterized by its ability to modulate the immune response and reduce inflammation by inhibiting the release of inflammatory mediators. The substance is typically administered topically, allowing for localized treatment with minimal systemic absorption. Fluocortolone acetate has a relatively high potency compared to other corticosteroids, making it effective in managing conditions such as eczema, dermatitis, and psoriasis. Its chemical structure includes a steroid nucleus, which is essential for its biological activity, and the acetate group enhances its solubility and stability. The compound is generally well-tolerated, but potential side effects may include skin thinning and local irritation with prolonged use. As with all corticosteroids, it is important to use fluocortolone acetate under medical supervision to minimize risks and ensure appropriate therapeutic outcomes.

Formula: C₂₄H₃₁FO₅

Synonyms:

• hydroxy-16-Methyl-pregna-1,4-diene-3,20-dione
• (6α,11β,16α)-21-(Acetyloxy)-6-fluoro-11-
• 21-Acetoxyfluocortolone
• 21-Acetoxy-6α-fluoro-11β-hydroxy-16α-Methylpregna-1,4-diene-3,20-dione
• Fluocortolone Acetate

Fluocortolone Acetate

Controlled Product

CAS: 1176-82-5

Applications Fluocortolone (F500500) derivative. Glucocorticoid.
References Breuer, et al.: Arzneim.-Forsch., 15, 50 (1965), Domenico, et al.: Arzneim.-Forsch., 15, 46 (1965), Gerhards, et al.: Acta Endocrinol., 68, 98 (1971)

Formula: C₂₄H₃₁FO₅

Color and Shape: Neat

Molecular weight: 418.5

Ref: TR-F500505

Fluocortolone Acetate

CAS: 1176-82-5

Formula: C₂₄H₃₁FO₄

Molecular weight: 418.5

Ref: ST-EA-CP-F102002