CAS 117620-87-8

8-O-Methyltetrangomycin

Description:

8-O-Methyltetrangomycin is a chemical compound that belongs to the class of tetracycline antibiotics, which are known for their broad-spectrum antibacterial activity. This substance is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. It exhibits properties such as antimicrobial efficacy against various Gram-positive and Gram-negative bacteria, making it a subject of interest in medicinal chemistry. The compound's mechanism of action typically involves inhibition of protein synthesis by binding to the bacterial ribosome. Additionally, 8-O-Methyltetrangomycin may possess unique pharmacokinetic properties, influencing its absorption, distribution, metabolism, and excretion in biological systems. Research into this compound may also explore its potential therapeutic applications, side effects, and resistance mechanisms. As with many antibiotics, the development of resistance is a significant concern, prompting ongoing studies to optimize its use and effectiveness in clinical settings.

Formula: C₂₀H₁₆O₅

InChI: InChI=1/C20H16O5/c1-20(24)8-10-6-7-12-17(15(10)13(21)9-20)19(23)11-4-3-5-14(25-2)16(11)18(12)22/h3-7,24H,8-9H2,1-2H3

InChI key: InChIKey=XZLGWJORNHETKI-HXUWFJFHSA-N

SMILES: O=C1C=2C3=C(C=CC2C(=O)C=4C1=CC=CC4OC)C[C@@](C)(O)CC3=O

Synonyms:

• (3R)-3,4-Dihydro-3-hydroxy-8-methoxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione
• MM 47755
• 6-Deoxy-8-O-methylrabelomycin
• 8-O-Methyltetrangomycin
• Benz[a]anthracene-1,7,12(2H)-trione, 3,4-dihydro-3-hydroxy-8-methoxy-3-methyl-, (3R)-
• 6-Deoxy-8-O-methylrabelomycin (MM 47755)
• (-)-3,4-Dihydro-3-hydroxy-8-methoxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione
• MM 47755 (6-Deoxy-8-O-methylrabelomycin)

6-Deoxy-8-O-methylrabelomycin

CAS: 117620-87-8

Formula: C₂₀H₁₆O₅

Purity: 81.36%

Color and Shape: Brownish. Solid

Molecular weight: 336.0

Ref: 8R-CL0220

6-Deoxy-8-O-methylrabelomycin

CAS: 117620-87-8

6-Deoxy-8-O-methylrabelomycin is a useful organic compound for research related to life sciences.

Formula: C₂₀H₁₆O₅

Color and Shape: Solid

Molecular weight: 336.343

Ref: TM-T126278

6-Deoxy-8-O-methylrabelomycin

CAS: 117620-87-8

Formula: C₂₀H₁₆O₅

Purity: ≥ 97.0%

Color and Shape: Off-white to yellow solid

Molecular weight: 336.3

Ref: 7W-GK7261

MM 47755

CAS: 117620-87-8

MM 47755 is a natural compound that has demonstrated inhibitory activity against the enolate of glycopeptide antibiotics. It is an enantiopure molecule, which means it is composed of a single type of chiral center. MM 47755 is an inhibitor of bacterial enzymes that are involved in the synthesis and degradation of glycopeptide antibiotics. MM 47755 binds to these enzymes (enolases) in a manner similar to those of the natural substrate, slowing down their metabolic activity and leading to inhibition.

Formula: C₂₀H₁₆O₅

Purity: Min. 95%

Molecular weight: 336.34 g/mol

Ref: 3D-SEA62087