CAS 117621-64-4

rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic acid

Description:

The chemical substance known as rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic acid, with the CAS number 117621-64-4, is characterized by its complex molecular structure, which includes multiple functional groups such as a dioxane ring, a hexenoic acid moiety, and a chlorophenyl substituent. This compound exhibits stereochemistry, indicated by the specific configuration of its chiral centers, which can influence its biological activity and interactions. The presence of hydroxyl groups suggests potential for hydrogen bonding, affecting solubility and reactivity. Additionally, the hexenoic acid component implies that it may participate in various chemical reactions typical of unsaturated carboxylic acids, such as addition reactions. The chlorophenyl group may impart specific electronic properties, influencing the compound's overall reactivity and potential applications in medicinal chemistry or as a synthetic intermediate. Overall, this substance's unique structural features contribute to its potential utility in various chemical and pharmaceutical contexts.

Formula: C₂₂H₂₃ClO₅

InChI: InChI=1/C22H23ClO5/c23-18-11-6-4-9-16(18)22-27-14-15(8-2-1-3-13-20(25)26)21(28-22)17-10-5-7-12-19(17)24/h1-2,4-7,9-12,15,21-22,24H,3,8,13-14H2,(H,25,26)/b2-1-/t15-,21+,22+/s2

InChI key: InChIKey=WHUIENZXNGAHQI-KGHIPOOSNA-N

SMILES: C(/C=C\CCC(O)=O)[C@@H]1[C@@H](O[C@@H](OC1)C2=C(Cl)C=CC=C2)C3=C(O)C=CC=C3

Synonyms:

• (4Z)-6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid
• (4Z)-6-[(2S,4S,5R)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid
• 4-Hexenoic acid, 6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-, (4Z)-rel-
• 4-Hexenoic acid, 6-[2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-, [2α,4α,5α(Z)]-
• Ici 191606
• Ici 192,605
• rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic acid

ICI 192605

CAS: 117621-64-4

Formula: C₂₂H₂₃ClO₅

Molecular weight: 402.87

Ref: 7W-GK8056

ICI 192605

CAS: 117621-64-4

ICI 192605 is a leukotriene receptor antagonist, which is a synthetic compound that specifically inhibits leukotriene activity. Leukotrienes are lipid compounds derived from arachidonic acid through the 5-lipoxygenase pathway. ICI 192605 functions by selectively blocking the cysteinyl leukotriene receptor 1 (CysLT1), thereby preventing leukotrienes from binding to this receptor.

Formula: C₂₂H₂₃ClO₅

Purity: Min. 95%

Molecular weight: 402.87 g/mol

Ref: 3D-BI178670

ICI 192605

CAS: 117621-64-4

ICI 192605 is a potent thromboxane A2 receptor (TP receptor) antagonist.

Formula: C₂₂H₂₃ClO₅

Color and Shape: Solid

Molecular weight: 402.87

Ref: TM-T27575