CAS 117671-02-0

Methyl 2,6-difluoro-3-pyridinecarboxylate

Description:

Methyl 2,6-difluoro-3-pyridinecarboxylate is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing nitrogen. The presence of two fluorine atoms at the 2 and 6 positions of the pyridine ring significantly influences its chemical properties, including increased electronegativity and potential reactivity. The carboxylate functional group, derived from the carboxylic acid, contributes to its acidity and solubility in polar solvents. As a methyl ester, it exhibits typical ester characteristics, such as being less polar than the corresponding acid. This compound is likely to be used in various applications, including pharmaceuticals and agrochemicals, due to its potential biological activity and ability to serve as a building block in synthetic chemistry. Its molecular structure suggests that it may participate in nucleophilic substitution reactions, making it a versatile intermediate in organic synthesis. Safety data should be consulted for handling, as fluorinated compounds can exhibit unique toxicological profiles.

Formula: C₇H₅F₂NO₂

InChI: InChI=1S/C7H5F2NO2/c1-12-7(11)4-2-3-5(8)10-6(4)9/h2-3H,1H3

InChI key: InChIKey=FTFGRVXYRDOUJN-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(F)N=C(F)C=C1

Synonyms:

• 3-Pyridinecarboxylic acid, 2,6-difluoro-, methyl ester
• Methyl 2,6-difluoro-3-pyridinecarboxylate
• 2,6-Difluoro-3-pyridinecarboxylic acid methyl ester
• Methyl 2,6-difluoronicotinate
• Methyl 2,6-difluoropyridine-3-carboxylate
• 2,6-Difluoro-3-pyridine-carboxylic acid Methyl ester
• 2,6-Difluoronicotinic acid Methyl ester

3-Pyridinecarboxylicacid, 2,6-difluoro-, methyl ester

CAS: 117671-02-0

Formula: C₇H₅F₂NO₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 173.1169

Ref: IN-DA0077KT

Methyl 2,6-difluoropyridine-3-carboxylate

CAS: 117671-02-0

Methyl 2,6-difluoropyridine-3-carboxylate

Formula: C₇H₅F₂NO₂

Purity: 95%

Color and Shape: low melting solid

Molecular weight: 173.12g/mol

Ref: 54-PC200403

2,6-Difluoro-nicotinic acid methyl ester

CAS: 117671-02-0

Formula: C₇H₅F₂NO₂

Purity: 98%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 173.119

Ref: 10-F316680

Methyl 2,6-difluoronicotinate

CAS: 117671-02-0

Methyl 2,6-difluoronicotinate is a regioselective dopamine receptor antagonist. It is a carboxylic acid that reacts with esters to form a nucleophilic anion. Methyl 2,6-difluoronicotinate has been shown to be an effective dopamine D2 receptor antagonist in rats and monkeys. This drug was also able to inhibit the binding of dopamine to the D3 receptor in rat striatal synaptosomes. The regioselectivity of this drug allows for preferential binding at the D2 receptor over other sites such as the D1 or D4 receptors.

Formula: C₇H₅F₂NO₂

Purity: Min. 95%

Molecular weight: 173.12 g/mol

Ref: 3D-FM100742