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CAS 117678-37-2

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Levofloxacin N-Oxide

Description:
Levofloxacin N-Oxide is a derivative of the fluoroquinolone antibiotic levofloxacin, characterized by the presence of an N-oxide functional group. This modification can influence its pharmacological properties, including its antibacterial activity and pharmacokinetics. The compound typically exhibits broad-spectrum antibacterial activity against various Gram-positive and Gram-negative bacteria, making it useful in treating infections. Levofloxacin N-Oxide is known for its mechanism of action, which involves inhibiting bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial DNA replication and repair. In terms of physical properties, it is generally a crystalline solid, soluble in polar solvents, and may exhibit stability under specific conditions. The compound's safety profile and potential side effects are similar to those of other fluoroquinolones, necessitating careful consideration in clinical use. As with any pharmaceutical compound, its efficacy and safety should be evaluated through rigorous clinical studies.
Formula:C18H20FN3O5
Synonyms:
  • Levofloxacin N-Oxide 2
  • (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
  • (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-Piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-Benzoxazine-6-Varboxylic Acid
  • (R)-Levofloxacin N-Oxide
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50
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90
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95
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100
Found 3 products.