CAS 1177-87-3

Dexamethasone acetate

Description:

Dexamethasone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressant properties. It is a derivative of dexamethasone, characterized by the addition of an acetate group, which enhances its solubility and bioavailability. This compound is typically administered via injection or as an oral formulation and is used to treat a variety of conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone acetate works by inhibiting the release of inflammatory mediators and modulating the immune response. It has a relatively long half-life compared to other corticosteroids, allowing for less frequent dosing. The substance is known for its potency and effectiveness, but it can also lead to side effects such as increased blood sugar levels, weight gain, and potential suppression of the adrenal gland with prolonged use. As with all corticosteroids, careful monitoring is essential to mitigate adverse effects and ensure therapeutic efficacy.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key: InChIKey=AKUJBENLRBOFTD-RPRRAYFGSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COC(C)=O)=O)O)[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 16α-Methyl-9α-fluoroprednisolone 21-acetate
• Dalalone DP
• Dalalone LA
• Decadron LA
• Decadronal
• Dectancyl
• Dex-Cortidelt acetate
• Dexa-Cortisyl
• Dexamethasone Acetate
• Dexamethasone-17-acetate
• Dexamethasoneacetate
• Fortecortin
• Fortecortin (crystal suspension)
• NSC 39471
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-

21-O-Acetyl dexamethasone

Controlled Product

CAS: 1177-87-3

21-O-Acetyl dexamethasone is a synthetic glucocorticoid that acts as a potent anti-inflammatory and immunosuppressive agent. It is used in the treatment of a wide range of conditions, including allergic reactions, skin disorders, and inflammatory bowel disease. The biological properties of this drug have been studied using an experimental model in rats. 21-O-Acetyl dexamethasone was found to be more effective than dexamethasone acetate in reducing allergic symptoms. The surface methodology has also been studied for the detection of this drug. This method is based on the reaction mechanism between the drug and matrix effect to produce fluorescent compounds that can be detected by ultraviolet (UV) light.

Formula: C₂₄H₃₁FO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 434.50 g/mol

Ref: 3D-FA17017

Dodecahydro-3H-cyclopenta2-oxoethyl Acetate Dexamethasone

Controlled Product

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Color and Shape: Neat

Molecular weight: 434.5

Ref: TR-A298525

Dexamethasone acetate

CAS: 1177-87-3

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of can

Formula: C₂₄H₃₁FO₆

Molecular weight: 434.5

Ref: 02-J63691