CAS 1177-87-3: Dexamethasone acetate

Description: Dexamethasone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressant properties. It is a derivative of dexamethasone, characterized by the addition of an acetate group, which enhances its solubility and bioavailability. This compound is typically administered via injection or as an oral formulation and is used to treat a variety of conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone acetate works by inhibiting the release of inflammatory mediators and modulating the immune response. It has a relatively long half-life compared to other corticosteroids, allowing for less frequent dosing. The substance is known for its potency and effectiveness, but it can also lead to side effects such as increased blood sugar levels, weight gain, and potential suppression of the adrenal gland with prolonged use. As with all corticosteroids, careful monitoring is essential to mitigate adverse effects and ensure therapeutic efficacy.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key: InChIKey=AKUJBENLRBOFTD-RPRRAYFGSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)COC(=O)C)C4(C)CC(O)C32F)C

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 16α-Methyl-9α-fluoroprednisolone 21-acetate
• Dalalone DP
• Dalalone LA
• Decadron LA
• Decadronal
• Dectancyl
• Dex-Cortidelt acetate
• Dexa-Cortisyl
• Dexamethasone Acetate
• Dexamethasone-17-acetate
• Dexamethasoneacetate
• Fortecortin
• Fortecortin (crystal suspension)
• NSC 39471
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-acetate

21-O-Acetyl dexamethasone

CAS: 1177-87-3

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• Formula: C₂₄H₃₁FO₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 434.50 g/mol

Dodecahydro-3H-cyclopenta2-oxoethyl Acetate Dexamethasone

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Neat
• Molecular weight: 434.5