CAS 1177141-67-1

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride

Description:

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide dihydrochloride is a chemical compound characterized by its complex structure, which includes an isoquinoline core, an aminoethyl side chain, and a sulfonamide functional group. This compound typically appears as a white to off-white crystalline solid and is soluble in water due to the presence of the sulfonamide and dihydrochloride moieties. It is often used in pharmaceutical research and development, particularly in the context of drug design and synthesis, owing to its potential biological activity. The presence of chlorine in the isoquinoline ring may influence its pharmacological properties, including its interaction with biological targets. As with many sulfonamides, this compound may exhibit antibacterial properties, although specific activity can vary based on structural modifications and the biological context. Safety and handling precautions should be observed, as with all chemical substances, to mitigate any potential hazards associated with its use.

Synonyms:

• CKI-7 2HCL
• CKI-7 DIHYDROCHLORIDE
• N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide dihydrochloride

CAS: 1177141-67-1

Formula: C₁₁H₁₄Cl₃N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.6718

Ref: IN-DA003S8N

CKI-7 dihydrochloride

CAS: 1177141-67-1

Formula: C₁₁H₁₂ClN₃O₂S·2HCl

Molecular weight: 358.67

Ref: 7W-GK8058

CKI-7

CAS: 1177141-67-1

CKI-7

Purity: ≥98%

Molecular weight: 358.67g/mol

Ref: 54-BUP07206

CKI-7

CAS: 1177141-67-1

CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.

Formula: C₁₁H₁₄Cl₃N₃O₂S

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 358.67

Ref: TM-T19913

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride

Controlled Product

CAS: 1177141-67-1

Applications Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hidaka, H., et al.: J. of Biol. Chem., 264, 9, 4924 (1989)

Formula: C₁₁H₁₂ClN₃O₂S·2ClH

Color and Shape: Neat

Molecular weight: 358.67

Ref: TR-A608851

CKI 7 dihydrochloride

CAS: 1177141-67-1

Inhibitor of casein kinase 1

Formula: C₁₁H₁₂ClN₃O₂S·2HCl

Purity: Min. 95%

Molecular weight: 358.67 g/mol

Ref: 3D-BC162796