CAS 1177261-85-6

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]methanone

Description:

The chemical substance known as [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]methanone, with the CAS number 1177261-85-6, is a complex organic compound characterized by its unique structural features. It contains a quinazoline moiety, which is known for its biological activity, particularly in medicinal chemistry. The presence of a piperazine ring contributes to its potential pharmacological properties, enhancing interactions with biological targets. Additionally, the tetrahydrofuran derivative indicates the presence of a cyclic ether, which may influence solubility and reactivity. The compound's functional groups, including the methanone and amino groups, suggest potential for hydrogen bonding and reactivity in various chemical environments. Overall, this substance is of interest in the field of drug discovery and development, particularly for its potential therapeutic applications, although specific biological activities and mechanisms would require further investigation through experimental studies.

Formula: C₂₀H₂₇N₅O₄

InChI: InChI=1S/C20H27N5O4/c1-12-4-5-15(29-12)19(26)24-6-8-25(9-7-24)20-22-14-11-17(28-3)16(27-2)10-13(14)18(21)23-20/h10-12,15H,4-9H2,1-3H3,(H2,21,22,23)/t12-,15?/m0/s1

InChI key: InChIKey=HKXGJHSYGLAWLN-SFVWDYPZSA-N

SMILES: NC=1C2=C(N=C(N1)N3CCN(C(=O)C4O[C@@H](C)CC4)CC3)C=C(OC)C(OC)=C2

Synonyms:

• [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]methanone
• Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]-

Terazosin EP Impurity I (Mixture of Diastereomers)

CAS: 1177261-85-6

Formula: C₂₀H₂₇N₅O₄

Color and Shape: White To Off-White Solid

Molecular weight: 401.47

Ref: 4Z-T-755

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]methanone

Controlled Product

CAS: 1177261-85-6

Formula: C₂₀H₂₇N₅O₄

Color and Shape: Neat

Molecular weight: 401.46

Ref: TR-A605025

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]methanone-d8

Controlled Product

CAS: 1177261-85-6

Formula: C₂₀D₈H₁₉N₅O₄

Color and Shape: Neat

Molecular weight: 409.509

Ref: TR-A605027

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]-methanone

CAS: 1177261-85-6

Furegrelate is an analytical reference standard for the hydroxylation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl[(5S)-tetrahydro-5-methyl-2-furanyl]-methanone. Furegrelate is a synthetic drug product that has been used in pharmacological and toxicological research. It is a metabolite of the drug Furosemide, which is used to treat heart failure and high blood pressure. Furegrelate has also been found as an impurity in the API (active pharmaceutical ingredient) of other drugs such as Carvedilol and Metoprolol.

Formula: C₂₀H₂₇N₅O₄

Purity: Min. 95%

Molecular weight: 401.46 g/mol

Ref: 3D-IA63848

Terazosin EP Impurity I

CAS: 1177261-85-6

Formula: C₂₀H₂₇N₅O₄

Molecular weight: 401.5

Ref: ST-EA-CP-T17009