CAS 117796-52-8

11-(1-Acetyl-4-piperidylidene)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine

Description:

11-(1-Acetyl-4-piperidylidene)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine, with CAS number 117796-52-8, is a chemical compound that belongs to a class of heterocyclic compounds. It features a complex bicyclic structure that incorporates both a piperidine and a chloro group, contributing to its unique chemical properties. The presence of the acetyl group suggests potential reactivity and the ability to participate in various chemical reactions, such as acylation or nucleophilic substitutions. This compound may exhibit biological activity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Its structural characteristics may influence its solubility, stability, and interaction with biological targets. As with many compounds of this nature, understanding its properties requires further investigation through experimental studies, including its synthesis, characterization, and potential applications in drug discovery or other fields. Safety and handling precautions should be observed due to the presence of chlorine and the potential for biological activity.

Formula: C₂₁H₂₁ClN₂O

InChI: InChI=1/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3

SMILES: CC(=O)N1CCC(=C2c3ccc(cc3CCc3cccnc23)Cl)CC1

Synonyms:

• Sch-37370
• 1-[4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl]ethanone

N-Acetyl Desloratadine (1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]ethanone)

CAS: 117796-52-8

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₁H₂₁ClN₂O

Color and Shape: White Off-White Solid

Molecular weight: 352.13424

Ref: 45-1A01670

Sch 37370

CAS: 117796-52-8

Formula: C₂₁H₂₁ClN₂O

Purity: 99%

Molecular weight: 352.8572

Ref: IN-DA008VXI

SCH-37370

CAS: 117796-52-8

SCH-37370

Purity: ≥98%

Molecular weight: 352.86g/mol

Ref: 54-BUP07193

N-Acetyl Desloratadine

CAS: 117796-52-8

Formula: C₂₁H₂₁ClN₂O

Color and Shape: White To Off-White Solid

Molecular weight: 352.86

Ref: 4Z-L-1041

SCH-37370

CAS: 117796-52-8

SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.

Formula: C₂₁H₂₁ClN₂O

Purity: 99.07%

Color and Shape: Solid

Molecular weight: 352.86

Ref: TM-T19686

N-Acetyldesloratadine

Controlled Product

CAS: 117796-52-8

Applications N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine (D290250), Nonsedating-type histamine H1-receptor antagonist.
References Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001);

Formula: C₂₁H₂₁ClN₂O

Color and Shape: Neat

Molecular weight: 352.86

Ref: TR-A168470

N-Acetyldesloratadine

CAS: 117796-52-8

N-Acetyldesloratadine is a second generation antihistamine that has high affinity for histamine H1 receptors. It is an orally active drug that is used to treat allergic rhinitis, chronic idiopathic urticaria, and pruritus. N-Acetyldesloratadine has been shown to inhibit platelet aggregation in vitro and in vivo. This activity may be due to the drug's ability to bind with high affinity to histamine receptor sites on the membranes of platelets, thereby inhibiting the binding of adenosine diphosphate (ADP) to its receptor site. N-Acetyldesloratadine also inhibits the release of serotonin from mast cells and basophils in vitro.

Formula: C₂₁H₂₁ClN₂O

Purity: Min. 95%

Molecular weight: 352.9 g/mol

Ref: 3D-SEA79652

Desloratadine N-Acetyl Impurity

CAS: 117796-52-8

Formula: C₂₁H₂₁ClN₂O

Molecular weight: 352.86

Ref: ST-EA-CP-D15023