CAS 117811-18-4
:5,6-Dehydro-N-methyl Desloratadine
Description:
5,6-Dehydro-N-methyl Desloratadine is a derivative of desloratadine, which is an antihistamine commonly used to treat allergic symptoms. This compound is characterized by its structural modifications that enhance its pharmacological properties. It typically exhibits a high affinity for peripheral H1 receptors, leading to effective antihistaminic activity while minimizing central nervous system effects, thus reducing sedation. The presence of the dehydro group suggests alterations in its electronic and steric properties, potentially influencing its metabolic stability and bioavailability. As a member of the tricyclic antihistamine class, it may also possess anti-inflammatory properties. The compound is generally considered to have a favorable safety profile, with side effects being relatively mild compared to first-generation antihistamines. Its solubility and stability in various solvents can vary, which is important for formulation in pharmaceutical applications. Overall, 5,6-Dehydro-N-methyl Desloratadine represents a significant advancement in antihistamine development, aiming for improved efficacy and reduced side effects.
Formula:C20H19ClN2
Synonyms:- Desloratadine Dehydro N-Methyl Impurity
- Desloratadine Impurity 13
- 5,6-Dehydro-N-methyl Desloratadine
- 8-chloro-11-(1-Methyl-4-piperidinylidene)-
- Loratadine Impurity 32
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Found 3 products.
5,6-Dehydro-N-methyl Desloratadine
CAS:Controlled Product<p>Applications A derivative of Loratadine as dual antagonist of platelet activating factor (PAF) and histamine. An antiinflammatory agent.<br>References Piwinski, J.J., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Formula:C20H19ClN2Color and Shape:NeatMolecular weight:322.831
