CAS 117857-45-1

Loreclezole

Description:

Loreclezole, with the CAS number 117857-45-1, is a chemical compound that belongs to the class of benzodiazepines. It is primarily recognized for its role as a selective modulator of the GABA (gamma-aminobutyric acid) receptor, which is crucial for inhibitory neurotransmission in the central nervous system. This compound exhibits anxiolytic and anticonvulsant properties, making it of interest in pharmacological research. Loreclezole is characterized by its ability to enhance the effects of GABA, thereby promoting sedation and muscle relaxation. Its chemical structure features a benzodiazepine core, which is common among compounds in this class, contributing to its biological activity. Additionally, Loreclezole has been studied for its potential neuroprotective effects and its role in modulating various neurological conditions. As with many compounds affecting the central nervous system, careful consideration of dosage and potential side effects is essential in its application. Overall, Loreclezole represents a significant area of interest in medicinal chemistry and neuropharmacology.

Formula: C₁₀H₆Cl₃N₃

InChI: InChI=1S/C10H6Cl3N3/c11-7-1-2-8(9(12)3-7)10(13)4-16-6-14-5-15-16/h1-6H/b10-4-

InChI key: InChIKey=XGLHZTBDUXXHOM-WMZJFQQLSA-N

SMILES: C(=C\N1C=NC=N1)(\Cl)/C2=C(Cl)C=C(Cl)C=C2

Synonyms:

• (Z)-1-(beta,2,4-Trichlorostyryl)-1H-1,2,4-triazole
• 1-[(1Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole
• 1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole
• 1H-1,2,4-Triazole, 1-(2-chloro-2-(2,4-dichlorophenyl)ethenyl)-, (Z)-
• 1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-
• Loreclezol
• Loreclezol [INN-Spanish]
• Loreclezole [USAN:INN:BAN]
• Loreclezolum
• Loreclezolum [INN-Latin]
• R 72063
• Unii-6Dj32Stz5W

Loreclezole hydrochloride

CAS: 117857-45-1

Formula: C₁₀H₆Cl₃N₃

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 274.5337

Ref: IN-DA007QPR

Loreclezole

CAS: 117857-45-1

Loreclezole

Purity: ≥98%

Molecular weight: 274.53g/mol

Ref: 54-BUP10260

Loreclezole

CAS: 117857-45-1

Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.

Formula: C₁₀H₆Cl₃N₃

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 274.53

Ref: TM-T5375

Loreclezole

CAS: 117857-45-1

Loreclezole is an antiepileptic drug, which is a synthetic compound with therapeutic effects on the central nervous system. This drug is classified as a 1,2-benzothiazole derivative and primarily impacts neuronal activity. Its source is entirely synthetic, developed through chemical synthesis processes designed to target specific neural pathways involved in seizure activity.

Formula: C₁₀H₆Cl₃N₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 274.53 g/mol

Ref: 3D-SEA85745