CAS 1179-69-7

Thiethylperazine Maleate

Description:

Thiethylperazine maleate is a pharmaceutical compound primarily used as an antiemetic and antipsychotic agent. It belongs to the class of phenothiazines, which are known for their ability to block dopamine receptors in the brain, thereby alleviating nausea and vomiting. The maleate salt form enhances its solubility and stability, making it suitable for various formulations. This compound typically appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its administration in liquid forms. Its pharmacological effects include sedation and the reduction of anxiety, making it useful in treating conditions such as schizophrenia and severe nausea. However, like other phenothiazines, thiethylperazine maleate may have side effects, including sedation, dry mouth, and potential extrapyramidal symptoms. It is essential for healthcare providers to monitor patients for these effects and adjust dosages accordingly. Overall, thiethylperazine maleate is a valuable medication in the therapeutic arsenal for managing specific psychiatric and gastrointestinal disorders.

Formula: C₄H₂O₄

InChI: InChI=1/C22H29N3S2.2C4H4O4/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24;2*5-3(6)1-2-4(7)8/h4-5,7-10,17H,3,6,11-16H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI key: InChIKey=FBZFLZSBKWFFRD-BTJKTKAUSA-N

SMILES: C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SCC)C3.C(=C\C(O)=O)\C(O)=O

Synonyms:

• 10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate
• 10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate (1:2)
• 10H-Phenothiazine, 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-, (2Z)-2-butenedioate (1:2)
• 2-(Ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine dimaleate
• 2-(Ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine maleate (1:2)
• 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
• 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioate]
• 2-Ethylmercapto-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine dimaleate
• 3-Ethylmercapto-10-(1'-methylpiperazinyl-4'-propyl)phenothiazine dimaleate
• Gs-95
• Norzine
• Nsc-130044
• Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, dimaleate
• Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, maleate (1:2)
• Thiethylperazine di(hydrogen maleate)
• Thiethylperazine dimaleate
• Thiethylperazine maleate [USAN]
• Tietylperazine malate
• Tietylperazine maleate
• Torecan
• Torecan bimaleate
• Torecan dimaleate
• Torecan maleate
• Toresten
• Tresten
• Unii-Ruk64Cf26E
• Thiethylperazine maleate
• 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1
• torecanmaleate
• torecanbimaleate
• 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate
• 2-butenedioate
• (z)-10h-phenothiazin
• 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazindimaleat
• 3-ethylmercapto-10-(1’-methylpiperazinyl-4’-propyl)phenothiazinedimaleate
• 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinemaleate(1:2
• 2-ethylmercapto-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazinedimaleate
• thiethylperazinemaleate
• thiethylperazinedimaleate
• 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2)
• THIETHYLPERAZINE MALEATE (200 MG)

Thiethylperazine Maleate

CAS: 1179-69-7

Color and Shape: Neat

Ref: 61-FOR1599.00

Thiethylperazine dimaleate

CAS: 1179-69-7

Thiethylperazine dimaleate

Purity: ≥98%

Molecular weight: 631.76g/mol

Ref: 54-BUP10234

Thiethylperazine Dimaleate

Controlled Product

CAS: 1179-69-7

Applications Thiethylperazine Maleate is used a phenothiazine derivative used in the treatment of multi-drug resistant (MDR) bacterial infections. Antibacterial.
References Kolaczkowski, M. et al.: Int. J. Antimicrob. Agents, 22, 279 (2003); Murray, M. et al.: Chem. Res. Toxicol., 2, 240 (1989);

Formula: C₂₂H₂₉N₃S₂·2C₄H₄O₄

Color and Shape: Neat

Molecular weight: 631.76

Ref: TR-T344505

Thiethylperazine dimaleate

CAS: 1179-69-7

Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor.

Formula: C₃₀H₃₇N₃O₈S₂

Purity: 99.07%

Color and Shape: Solid

Molecular weight: 631.76

Ref: TM-T17072

Thiethylperazine Maleate (DISCONTINUED)

CAS: 1179-69-7

Drugs containing a phenothiazine ring system (whether or not hydrogenated) not further fused, nesoi

Formula: C₂₂H₂₉N₃S₂·2C₄H₄O₄

Color and Shape: Powder

Molecular weight: 631.20221

Ref: 45-1658008