CAS 118-08-1

(-)-Hydrastine

Description:

(-)-Hydrastine is an alkaloid derived from the plant Hydrastis canadensis, commonly known as goldenseal. It is characterized by its complex molecular structure, which includes multiple chiral centers, contributing to its stereochemistry. This compound typically appears as a white to off-white crystalline powder and is known for its bitter taste. (-)-Hydrastine exhibits various biological activities, including antimicrobial and anti-inflammatory properties, and has been studied for its potential therapeutic applications. It acts as a vasodilator and has been investigated for its effects on the cardiovascular system. The compound is soluble in alcohol and slightly soluble in water, which influences its formulation in medicinal preparations. Due to its pharmacological effects, (-)-Hydrastine is of interest in both traditional herbal medicine and modern pharmacology, although its use should be approached with caution due to potential side effects and interactions with other medications. As with many alkaloids, proper handling and dosage are essential to ensure safety and efficacy in its applications.

Formula: C₂₁H₂₁NO₆

InChI: InChI=1S/C21H21NO6/c1-22-7-6-11-8-15-16(27-10-26-15)9-13(11)18(22)19-12-4-5-14(24-2)20(25-3)17(12)21(23)28-19/h4-5,8-9,18-19H,6-7,10H2,1-3H3/t18-,19+/m1/s1

InChI key: InChIKey=JZUTXVTYJDCMDU-MOPGFXCFSA-N

SMILES: CN1[C@@]([C@@]2(C=3C(C(=O)O2)=C(OC)C(OC)=CC3)[H])(C4=C(C=C5C(=C4)OCO5)CC1)[H]

Synonyms:

• (-)-β-Hydrastine
• (1R,9S)-β-Hydrastine
• (3R)-6,7-dimethoxy-3-[(5R)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
• (3S)-6,7-dimethoxy-3-[(5R)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
• 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.
• 6,7-dimethoxy-3-(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one
• Hydrastine
• l-Hydrastine

Hydrastine

CAS: 118-08-1

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Formula: C₂₁H₂₁NO₆

Color and Shape: White Powder

Molecular weight: 383.13689

Ref: 45-1313210

Hydrastine

CAS: 118-08-1

Hydrastine

Purity: ≥98%

Molecular weight: 383.39g/mol

Ref: 54-BUP05960

Hydrastine

CAS: 118-08-1

Formula: C₂₁H₂₁NO₆

Molecular weight: 383.40

Ref: 7W-GY5768

Hydrastine

CAS: 118-08-1

Formula: C₂₁H₂₁NO₆

Purity: 95%~99%

Molecular weight: 383.4

Ref: BP-BP0744

Hydrastine

Controlled Product

CAS: 118-08-1

Formula: C₂₁H₂₁NO₆

Color and Shape: Neat

Molecular weight: 383.39

Ref: 04-C14220500

Hydrastine

CAS: 118-08-1

Hydrastine ((-)-β-Hydrastine) is a natural alkaloid that is present in Hydrastis Canadensis.

Formula: C₂₁H₂₁NO₆

Purity: 98.16% - 99.86%

Color and Shape: Solid

Molecular weight: 383.39

Ref: TM-TQ0160

Hydrastine

CAS: 118-08-1

Natural alkaloid

Formula: C₂₁H₂₁NO₆

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 383.4

Ref: 5G-89511

(-)-Hydrastine

CAS: 118-08-1

(-)-Hydrastine is a naturally occurring isoquinoline alkaloid, which is primarily sourced from the roots and rhizomes of the plant Hydrastis canadensis, commonly known as goldenseal. This compound is extracted as part of phytochemical investigations into the medicinal properties of traditional herbal remedies. Its mode of action involves interference with calcium channel pathways, which suggests potential vasodilatory and antispasmodic effects. Furthermore, it has been studied for various biochemical interactions that may contribute to its pharmacological effects.

Formula: C₂₁H₂₁NO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 383.39 g/mol

Ref: 3D-FH61654