CAS 118-42-3: Hydroxychloroquine

Description: Hydroxychloroquine is a synthetic compound primarily used as an antimalarial and immunomodulatory agent. It belongs to the class of drugs known as 4-aminoquinolines and is characterized by its ability to inhibit the growth of certain parasites, particularly Plasmodium species, which cause malaria. The chemical structure of hydroxychloroquine includes a hydroxyl group, which enhances its solubility and bioavailability compared to its predecessor, chloroquine. It is also utilized in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus due to its immunosuppressive properties. Hydroxychloroquine functions by interfering with the communication of immune cells and modulating inflammatory responses. The substance is generally well-tolerated, but it can have side effects, including gastrointestinal disturbances and potential retinal toxicity with long-term use. Its mechanism of action involves the alteration of lysosomal pH, which affects antigen processing and presentation. Hydroxychloroquine has gained attention in recent years for its potential role in treating viral infections, although its efficacy in this context remains under investigation.

Formula: C₁₈H₂₆ClN₃O

InChI: InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)

InChI key: InChIKey=XXSMGPRMXLTPCZ-UHFFFAOYSA-N

SMILES: ClC=1C=CC=2C(=NC=CC2NC(C)CCCN(CC)CCO)C1

Synonyms:

• (.+-.)-Hydroxychloroquine
• 2-([4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino)ethan-1-ol
• 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol
• 7-Chloro-4-[4'-[ethyl (2''-hydroxyethyl) amino]-1'-methylbutylamino]quinoline
• 7-Chloro-4-[4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino]quinoline
• 7-Chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
• Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-
• Hidroxicloroquina
• Hydroxychlorochin
• Oxichloroquine
• Oxychlorochin
• Oxychloroquine
• Racemic Hydroxychloroquine
• Win 1258
• Win 1258-2
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-

2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol sulfate

CAS: 118-42-3

• Formula: C₁₈H₂₆ClN₃O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 335.8715399999999

Hydroxychloroquine

CAS: 118-42-3

• Purity: 99%
• Molecular weight: 335.87g/mol

Hydroxychloroquine

CAS: 118-42-3

• Purity: 99.02%
• Molecular weight: 335.87g/mol

Hydroxychloroquine Sulfate

CAS: 118-42-3747-36-4

• Formula: C₁₈H₂₆ClN₃O·H₂SO₄
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 433.95

Hydroxychloroquine

CAS: 118-42-3

HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.

• Formula: C₁₈H₂₆ClN₃O
• Purity: 99.79%
• Color and Shape: Solid
• Molecular weight: 335.87

HYDROXYCHLOROQUINE

CAS: 118-42-3

• Purity: 95%
• Molecular weight: 335.8800048828125

Hydroxychloroquine

CAS: 118-42-3

Applications An antimalarial; antirheumatic; lupus erythematosus suppressant. It is a COVID19-related research product. References Yarden, …

• Formula: C₁₈H₂₆ClN₃O
• Color and Shape: Neat
• Molecular weight: 335.87

Hydroxy Choroquine-D5 Phosphate Salt

CAS: 118-42-36168-85-0 645406-23-1

• Formula: C₁₈H₂₁D₅ClN₃O· 2(H₃PO₄)
• Color and Shape: Neat
• Molecular weight: 536.88

Hydroxychloroquine

CAS: 118-42-3

Hydroxychloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic …

• Formula: C₁₈H₂₆ClN₃O
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 335.87 g/mol