CAS 118-47-8

1-(4′-Sulfophenyl)-3-carboxy-5-pyrazolone

Description:

1-(4′-Sulfophenyl)-3-carboxy-5-pyrazolone, commonly known as Sulfopyrazone, is an organic compound characterized by its pyrazolone structure, which includes a sulfonic acid group and a carboxylic acid group. This compound is typically a yellow to orange crystalline solid that is soluble in water due to the presence of the sulfonic acid group, which enhances its hydrophilicity. It exhibits strong acidic properties and can participate in various chemical reactions, including those involving nucleophiles and electrophiles. Sulfopyrazone is primarily used in the pharmaceutical industry, particularly as a non-steroidal anti-inflammatory drug (NSAID) and as a uricosuric agent for the treatment of gout. Its mechanism of action involves the inhibition of prostaglandin synthesis, which helps reduce inflammation and pain. Additionally, it has applications in analytical chemistry as a reagent for the determination of certain metal ions. Safety data indicates that it should be handled with care, as it may cause skin and eye irritation.

Formula: C₁₀H₈N₂O₆S

InChI: InChI=1S/C10H8N2O6S/c13-9-5-8(10(14)15)11-12(9)6-1-3-7(4-2-6)19(16,17)18/h1-4H,5H2,(H,14,15)(H,16,17,18)

InChI key: InChIKey=TYCNXOAPQGVAQU-UHFFFAOYSA-N

SMILES: O=C1N(N=C(C(O)=O)C1)C2=CC=C(S(=O)(=O)O)C=C2

Synonyms:

• 1-(4'-sulfophenyl-)-3-Carboxy-5-Pyrazolone
• 1-(4-Sulfophenyl)-5-pyrazolone-3-carboxylic acid
• 1-(4-Sulphophenyl)-3-Carboxy-5-Pyrazolone
• 1-(4′-Sulfophenyl)-3-carboxypyrazolone-5
• 1-(4′-Sulfophenyl)pyrazol-5-one-3-carboxylic acid
• 1-(p-Sulfophenyl)-5-pyrazolone-3-carboxylic acid
• 1-Phenyl-4′-sulfo-5-pyrazolone-3-carboxylic acid
• 1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-
• 2-Pyrazoline-3-carboxylic acid, 5-oxo-1-(p-sulfophenyl)-
• 3-Carboxy-1-(4-sulfophenyl)-2-pyrazolin-5-one
• 3-Carboxy-1-(4-sulfophenyl)-5-pyrazolone
• 3-Carboxy-1-(p-sulfophenyl)-5-pyrazolone
• 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylic acid
• 5-Oxo-1-(p-sulfophenyl)-2-pyrazoline-3-carboxylic acid
• 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid
• Carboxypyrazolic acid
• NSC 50665
• NSC 51118

5-Oxo-1-(4-sulfophenyl)-2,5-dihydro-1H-pyrazole-3-carboxylic acid

CAS: 118-47-8

Formula: C₁₀H₈N₂O₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 284.2453

Ref: IN-DA00814X

5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

CAS: 118-47-8

5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

Purity: 95%

Molecular weight: 284.25g/mol

Ref: 54-OR1070620

5-oxo-1-(4-sulfophenyl)-2,5-dihydro-1H-pyrazole-3-carboxylic acid

CAS: 118-47-8

Purity: 95%

Molecular weight: 284.2399902

Ref: 10-F633522

5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid

CAS: 118-47-8

5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid is a compound that has been shown to have anticancer activity. This drug has been shown to inhibit the growth of various cancer cell lines in vitro and in vivo. In addition, it has been shown to increase the number of microvessel density in mice with inflammatory diseases and reduce the level of inflammatory markers. 5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole 3 carboxylic acid is also an inhibitor of angiogenesis and vascular permeability, which may be due to its interaction with lipoprotein receptors on endothelial cells. It is synthesized by bacteria and causes color changes in certain dyes or colorants (e.g., methylene blue). The detection time for this compound is not known as

Formula: C₁₀H₈N₂O₆S

Purity: Min. 95%

Molecular weight: 284.25 g/mol

Ref: 3D-FO129002