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CAS 1180-25-2

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Testosterone glucuronide

Description:
Testosterone glucuronide is a metabolite of testosterone, formed through the process of glucuronidation, where a glucuronic acid molecule is conjugated to testosterone. This modification enhances the solubility of testosterone, facilitating its excretion from the body, primarily via urine. The substance is characterized by its role in the metabolism of androgens and is often used as a biomarker in clinical and forensic settings to assess testosterone levels and monitor anabolic steroid use. Testosterone glucuronide is typically present in the body in low concentrations and can be detected using various analytical techniques, including liquid chromatography-tandem mass spectrometry (LC-MS/MS). Its presence in biological samples can provide insights into hormonal balance, endocrine function, and potential disorders related to testosterone metabolism. As a glucuronide, it is generally less biologically active than its parent compound, testosterone, but still plays a significant role in the pharmacokinetics of steroid hormones.
Formula:C25H36O8
InChI:InChI=1S/C25H36O8/c1-24-9-7-13(26)11-12(24)3-4-14-15-5-6-17(25(15,2)10-8-16(14)24)32-23-20(29)18(27)19(28)21(33-23)22(30)31/h11,14-21,23,27-29H,3-10H2,1-2H3,(H,30,31)/t14-,15-,16-,17-,18-,19-,20+,21-,23+,24-,25-/m0/s1
InChI key:InChIKey=NIKZPECGCSUSBV-HMAFJQTKSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
Synonyms:
  • (17Beta)-3-Oxoandrost-4-En-17-Yl Hexopyranosiduronic Acid
  • (17beta)-3-oxoandrost-4-en-17-yl beta-D-glucopyranosiduronic acid
  • (17β)-3-Oxoandrost-4-en-17-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
  • Androstane, β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv.
  • Epitestosterone glucuronide
  • Glucopyranosiduronic acid, 3-oxoandrost-4-en-17β-yl, β-<span class="text-smallcaps">D</span>-
  • Nsc 92192
  • Testosterone 17-glucosiduronate
  • Testosterone 17-glucuronide
  • Testosterone 17β-(β-<span class="text-smallcaps">D</span>-glucuronide)
  • See more synonyms
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Found 2 products.
  • Testosterone b-D-glucuronide
    Biosynth
    + Info

    Testosterone b-D-glucuronide

    Controlled Product
    CAS:
    Testosterone b-D-glucuronide (TbG) is a clinically relevant metabolite of testosterone. It is the glucuronide conjugate of testosterone, which means that it is formed by the addition of a glucuronic acid molecule to the hydroxyl group at position 17. TbG has been detected in human plasma, urine and feces. The concentration of TbG in these fluids reflects the levels of total testosterone in the body. TbG may also be used as a biomarker for assessing exposure to nonsteroidal anti-inflammatory drugs (NSAIDs). It has been shown that NSAIDs can form conjugates with glucuronic acid, leading to elevated concentrations of TbG in urine samples. TbG binds to monoclonal antibodies and is therefore used as a sample preparation step prior to analysis by polymerase chain reaction or flow assay.
    Formula:C25H36O8
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:464.55 g/mol

    Ref: 3D-MT08814

    1mg
    203.00€
    2mg
    305.00€
    5mg
    477.00€
    10mg
    679.00€
  • Testosterone Glucuronide
    Standalix
    + Info

    Testosterone Glucuronide

    CAS:
    Formula:C25H36O8
    Molecular weight:464.56

    Ref: ST-EA-CP-T37072

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