CAS 1180-71-8

limonin from citrus seeds

Description:

Limonin is a bitter compound primarily found in the seeds and pulp of citrus fruits, particularly in the genus Citrus, such as oranges and grapefruits. It is classified as a limonoid, which is a type of tetracyclic triterpenoid. The chemical structure of limonin contributes to its characteristic bitterness, which can affect the flavor profile of citrus products. Limonin is known for its potential health benefits, including antioxidant properties and possible anti-cancer effects, although more research is needed to fully understand its biological activities. It is relatively stable under acidic conditions but can degrade under alkaline conditions or prolonged heat. The compound is often studied for its role in food science, particularly in the context of citrus juice processing, where its presence can influence consumer acceptance. Additionally, limonin's CAS number, 1180-71-8, is used for identification in chemical databases and regulatory contexts. Overall, limonin is an important phytochemical with implications in both nutrition and food technology.

Formula: C₂₆H₃₀O₈

InChI: InChI=1/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20+,23-,24-,25+,26+/m0/s1

InChI key: InChIKey=KBDSLGBFQAGHBE-MSGMIQHVSA-N

SMILES: C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]56[C@@](CC2=O)(C(C)(C)O[C@]5(CC(=O)OC6)[H])[H])[H])C=7C=COC7)[H]

Synonyms:

• (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-8-(3-Furanyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H-oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione
• (4aS,6aR,8aR,8bR,12R,12aS,14aR,14bR)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-3H-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione
• (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-3H-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione
• 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-
• 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR-(2aalpha,4abeta,4bR,5aalpha,8alpha,8aalpha,10aalpha,10bR*,14aalpha))-
• 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-
• 11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-
• 11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, [2aR-(2aα,4aβ,4bR*,5aα,8α,8aα,10aα,10bR*,14aα)]-
• 11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-
• 7,16-Dioxo-7,16-dideoxylimondiol
• Ai3-37932
• Ccris 4047
• Citrolimonin
• Dictamnolactone
• Evodin
• Limonin
• Limonine
• Limonoic acid, di-delta-lactone
• Limonoic acid, di-δ-lactone
• Nsc 36508
• Obaculactone
• Obakulactone
• LIMONIN(RG)
• Limonin,Limonoic acid 3,19:16,17 dilactone
• LIMONIN(P)(CALL)
• Evodia lactone
• LIMONOIC ACID 3,19:16,17 DILACTONE
• LIMONIN(P)
• LiMonin, froM TetradiuM ruticarpuM
• Limonoate D-ring-lactone
• LiMone
• limonin from citrus seeds
• Limonin，Limonoate D-ring-lactone，Limonoic acid di-delta-lactone

Limonin

CAS: 1180-71-8

Formula: C₂₆H₃₀O₈

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 470.52

Ref: 3B-L0258

Limonin

CAS: 1180-71-8

Formula: C₂₆H₃₀O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 470.5116

Ref: IN-DA00395Y

Limonin

CAS: 1180-71-8

Limonin

Purity: 98%

Molecular weight: 470.51g/mol

Ref: 54-OR1013663

Limonin

CAS: 1180-71-8

Limonin

Purity: ≥98%

Molecular weight: 470.51g/mol

Ref: 54-BUP14574

Limonin

CAS: 1180-71-8

Formula: C₂₆H₃₀O₈

Purity: ≥ 95.0%

Color and Shape: White or almost white powder or crystals

Molecular weight: 470.51

Ref: 7W-GP4085

Limonin

CAS: 1180-71-8

Limonin is a widely used dietary supplement, one of the most prevalent citrus limonoids, which has antioxidant, anti-inflammatory, anticancer and anti-human immunodeficiency virus(HIV)activity. It induced a down regulation of TLR-2 ,TLR-4,TNF-α, TNF-α/IL-10,NF-κB and caspase. It showed the potent inhibition of CYP3A4, with IC50 values of 6.20 μM (CYP3A4/testosterone) and 19.10 μM (CYP3A4/midazolam).

Formula: C₂₆H₃₀O₈

Purity: 95%~99%

Molecular weight: 470.518

Ref: BP-BP0866

Limonin

CAS: 1180-71-8

Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.

Formula: C₂₆H₃₀O₈

Purity: 99.65% - 99.66%

Color and Shape: White To Slightly Off White Powder

Molecular weight: 470.51

Ref: TM-T2728

Limonin

CAS: 1180-71-8

Lactone

Formula: C₂₆H₃₀O₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 470.52

Ref: 5G-89379

Limonin

CAS: 1180-71-8

Applications Limonin is a limonoid extracted from various citrus plants. Bioactivity of Limonin have been revolved around its anti-HIV properties.
References Battinelli, L., et al.: Planta. Med., 69, 910 (2003); Kim, J., et al.: Food. Function., 4, 258 (2013); Chaudhary, P., et al.: Food. Chem., 135, 1667 (2012);

Formula: C₂₆H₃₀O₈

Color and Shape: Neat

Molecular weight: 470.51

Ref: TR-L461780

Limonin

CAS: 1180-71-8

Limonin is a triterpenoid limonoid, which is a naturally occurring compound primarily sourced from citrus fruits such as lemons, oranges, and other members of the Rutaceae family. As a bioactive compound, limonin is widely recognized for its bitter taste, commonly found in the seeds and pulp of these fruits.

Formula: C₂₆H₃₀O₈

Purity: Min. 98.5 Area-%

Color and Shape: Powder

Molecular weight: 470.51 g/mol

Ref: 3D-FL09973

LIMONIN

CAS: 1180-71-8

Purity: 98%

Molecular weight: 470.5180054

Ref: 10-F814417