CAS 1180-95-6: Sodium taurodeoxycholate
Description:Sodium taurodeoxycholate is a bile salt derived from deoxycholic acid, characterized by its amphipathic nature, which allows it to interact with both hydrophilic and hydrophobic substances. It is a sodium salt, meaning it contains sodium ions that contribute to its solubility in water. This compound plays a significant role in the emulsification of fats and is commonly used in biochemical and pharmaceutical applications, particularly in cell culture and as a surfactant. Its structure includes a steroid backbone with a hydroxyl group and a taurine moiety, which enhances its solubility and biological activity. Sodium taurodeoxycholate is known for its ability to disrupt cell membranes, making it useful in various laboratory techniques, including protein extraction and membrane protein solubilization. Additionally, it has been studied for its potential therapeutic effects, including its role in modulating cholesterol metabolism and its implications in drug delivery systems. However, its use must be carefully controlled due to potential cytotoxic effects at higher concentrations.
Formula:C26H45NO6S·Na
InChI:InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1
InChI key:InChIKey=DIBGIDJLTRRMCC-FVCKGWAHSA-N
SMILES:[Na].O=C(NCCS(=O)(=O)O)CCC(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C
- Synonyms:
- Cholane, ethanesulfonic acid deriv.
- Ethanesulfonic acid, 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt
- Sodium 2-(((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate
- Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethyl Sulfate
- Sodium 2-{[(3Alpha,5Beta,12Alpha)-3,12-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonate
- Sodium 3α,12α-dihydroxy-5β-cholanoyltaurate
- Sodium deoxytaurocholate
- Sodium taurodeoxycholate
- Sodium taurodesoxycholate
- Taurine, N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt
- See more synonyms
- Taurodeoxycholate sodium
- Taurodeoxycholic acid sodium salt
- Unii-5Pe424S83L