CAS 1180-95-6

Sodium taurodeoxycholate

Description:

Sodium taurodeoxycholate is a bile salt derived from deoxycholic acid, characterized by its amphipathic nature, which allows it to interact with both hydrophilic and hydrophobic substances. It is a sodium salt, meaning it contains sodium ions that contribute to its solubility in water. This compound plays a significant role in the emulsification of fats and is commonly used in biochemical and pharmaceutical applications, particularly in cell culture and as a surfactant. Its structure includes a steroid backbone with a hydroxyl group and a taurine moiety, which enhances its solubility and biological activity. Sodium taurodeoxycholate is known for its ability to disrupt cell membranes, making it useful in various laboratory techniques, including protein extraction and membrane protein solubilization. Additionally, it has been studied for its potential therapeutic effects, including its role in modulating cholesterol metabolism and its implications in drug delivery systems. However, its use must be carefully controlled due to potential cytotoxic effects at higher concentrations.

Formula: C₂₆H₄₅NO₆S·Na

InChI: InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1

InChI key: InChIKey=DIBGIDJLTRRMCC-FVCKGWAHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H].[Na]

Synonyms:

• Cholane, ethanesulfonic acid deriv.
• Ethanesulfonic acid, 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt
• Sodium 2-(((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate
• Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethyl Sulfate
• Sodium 2-{[(3Alpha,5Beta,12Alpha)-3,12-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonate
• Sodium 3α,12α-dihydroxy-5β-cholanoyltaurate
• Sodium deoxytaurocholate
• Sodium taurodeoxycholate
• Sodium taurodesoxycholate
• Taurine, N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt
• Taurodeoxycholate sodium
• Taurodeoxycholic acid sodium salt

Taurodeoxycholic Acid Sodium Salt

CAS: 1180-95-6

Formula: C₂₆H₄₄NNaO₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 521.6854

Ref: IN-DA008R3F

Taurodeoxycholate sodium salt

CAS: 1180-95-6

Taurodeoxycholate sodium salt

Purity: ≥98%

Molecular weight: 521.68g/mol

Ref: 54-BUP18227

Sodium Taurodeoxycholate

CAS: 1180-95-6

Formula: C26H45NO6S.Na

Purity: >98%

Color and Shape: Solid

Molecular weight: 522.7

Ref: 48-65-1014

Tauro-d4-deoxycholic AcidSodium Salt (Sodium Taurodeoxycholate)

CAS: 1180-95-6

Purity: 99 atom % D

Molecular weight: 525.71

Ref: 3U-D8182

Taurodeoxycholate sodium salt

CAS: 1180-95-6

Sodium taurodeoxylate, a bile salt, is used as an anionic detergent for isolating membrane proteins and inhibits inflammation.

Formula: C₂₆H₄₄NNaO₆S

Purity: 99.11% - 99.89%

Color and Shape: White Crystalline Powder

Molecular weight: 521.68

Ref: TM-TN2349

Taurodeoxycholic Acid Sodium Salt

Controlled Product

CAS: 1180-95-6

Applications Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
References Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),

Formula: C₂₆H₄₄NO₆S·Na

Color and Shape: Off-White

Molecular weight: 521.69

Ref: TR-T009005

Sodium taurodeoxycholate

CAS: 1180-95-6

Bile salts are intestinal natural detergents, their main function is to act as detergent in the digestive processes. The major action of a bile salt is to emulsify fats and oils. Bile salts are used in bacteriological culture media as selective inhibitory agent. Enteric bacteria are resistant to the bactericidal effects of bile salts. Anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Formula: C₂₆H₄₄NNaO₆S

Purity: Min. 97 Area-%

Molecular weight: 521.69 g/mol

Ref: 3D-S-6560

Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 95%

CAS: 1180-95-6

Formula: C₂₆H₄₄NO₆SNa

Purity: min. 95%

Color and Shape: White, Crystalline powder

Molecular weight: 521.69

Ref: SR-57861