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CAS 118045-71-9

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cyclopentenylcytosine 6-triphosphate

Description:
Cyclopentenylcytosine 6-triphosphate (CPT-CTP) is a nucleotide analog that features a cyclopentenyl group, which modifies the sugar component of the nucleoside. This compound is characterized by its triphosphate moiety, which is essential for its role in biochemical processes, particularly in nucleic acid synthesis and as a potential antiviral agent. The cyclopentenyl modification enhances the stability of the molecule against nucleases, making it a subject of interest in research focused on antiviral therapies and cancer treatment. CPT-CTP can be incorporated into RNA, where it may interfere with viral replication or cellular processes. Its unique structure allows it to exhibit distinct biochemical properties compared to natural nucleotides, influencing its interaction with polymerases and other enzymes involved in nucleic acid metabolism. The compound's CAS number, 118045-71-9, is a unique identifier that facilitates its identification in chemical databases and literature. Overall, cyclopentenylcytosine 6-triphosphate represents a significant tool in molecular biology and medicinal chemistry.
Formula:C10H16N3O13P3
InChI:InChI=1/C10H16N3O13P3/c11-7-1-2-13(10(16)12-7)6-3-5(8(14)9(6)15)4-24-28(20,21)26-29(22,23)25-27(17,18)19/h1-3,6,8-9,14-15H,4H2,(H,20,21)(H,22,23)(H2,11,12,16)(H2,17,18,19)/t6-,8-,9+/m1/s1
Synonyms:
  • Cpc TP
  • Cpec-TP
  • Cyclopentenyl cytosine 5'-triphosphate
  • Triphosphoric acid, P-((3-(4-amino-2-oxo-1(2H)-pyrimidinyl)-4,5-dihydroxy-1-cyclopenten-1-yl)methyl) ester, (3R-(3alpha,4beta,5beta))-
  • triphosphoric acid, mono[[(3R,4S,5R)-3-(4-amino-2-oxo-1(2H)-pyrimidinyl)-4,5-dihydroxy-1-cyclopenten-1-yl]methyl] ester
  • Cyclopentenylcytosine 6-triphosphate
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  • Cyclopentenylcytosine-5'-triphosphate Triethylamine Salt
    TRC
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    Cyclopentenylcytosine-5'-triphosphate Triethylamine Salt

    Controlled Product
    CAS:
    <p>Applications Cyclopentenylcytosine-5'-triphosphate is the active metabolite of Cyclopentenylcytosine (C989800); a nucleoside analog which exhibits antineoplastic activity against several murine and human tumors in tissue culture. Cyclopentenylcytosine-5'-triphosphate is also an inhibitor of cytidine-5'-triphosphate (CTP) synthetase causing a rapid depletion of intracellular cytidine nucleotides.<br>References Agbaria, R., et al.: Anal. Biochem., 213, 90 (1993); Agbaria, R., et al.: Oncol. Res., 9, 111 (1997); Bierau, J., et al.: Adv. Exp. Med. Biol., 486, 277 (2000)<br></p>
    Formula:C10H16N3O13P3•xC6H15N
    Color and Shape:Neat
    Molecular weight:479.17 + x(101.19)

    Ref: TR-C989805

    10mg
    31,279.00€