CAS 118058-75-6
:N,N-Didemethyl-6-O-methylerythromycin
Description:
N,N-Didemethyl-6-O-methylerythromycin is a semi-synthetic derivative of erythromycin, which is a macrolide antibiotic. This compound is characterized by its structural modifications that enhance its pharmacological properties compared to its parent compound. It typically exhibits antibacterial activity against a range of Gram-positive bacteria and some Gram-negative bacteria, making it useful in treating various infections. The modifications in its structure, particularly the dimethylation and methylation, can influence its solubility, stability, and bioavailability. N,N-Didemethyl-6-O-methylerythromycin is often studied for its potential in overcoming antibiotic resistance and improving therapeutic efficacy. As with other macrolides, it functions by inhibiting bacterial protein synthesis, thereby preventing bacterial growth. Its safety profile and side effects are generally similar to those of other macrolide antibiotics, but specific clinical data should be consulted for detailed information. Overall, this compound represents an important area of research in antibiotic development and modification.
Formula:C36H65NO13
InChI:InChI=1S/C36H65NO13/c1-13-24-36(10,43)29(40)19(4)26(38)17(2)15-35(9,45-12)31(50-33-27(39)23(37)14-18(3)46-33)20(5)28(21(6)32(42)48-24)49-25-16-34(8,44-11)30(41)22(7)47-25/h17-25,27-31,33,39-41,43H,13-16,37H2,1-12H3/t17-,18-,19+,20+,21-,22+,23+,24-,25+,27-,28+,29-,30+,31-,33+,34-,35-,36-/m1/s1
InChI key:InChIKey=JWCOYCBCUODHBU-QNPWSHAKSA-N
SMILES:O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@]1(OC)C)[C@H]3[C@H](O)[C@@H](N)C[C@@H](C)O3
Synonyms:- Erythromycin, N,N-didemethyl-6-O-methyl-
- N,N-Didemethyl-6-O-methylerythromycin
- N,N-Didemethylclarithromycin
- Oxacyclotetradecane, erythromycin deriv.
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