CAS 118068-30-7

Amylin (20-29) (human)

Description:

Amylin, specifically the fragment known as Amylin (20-29), is a peptide derived from the human amylin protein, which is co-secreted with insulin by pancreatic beta cells. This peptide plays a significant role in glucose metabolism and regulation of appetite. The CAS number 118068-30-7 identifies this specific fragment, which consists of a sequence of amino acids that contribute to its biological activity. Amylin (20-29) is known for its ability to inhibit gastric emptying, promote satiety, and modulate insulin action, making it relevant in the context of diabetes and obesity research. The peptide exhibits a propensity to form amyloid fibrils, which is a characteristic associated with the pathophysiology of type 2 diabetes. Its structure includes hydrophobic regions that facilitate interactions with cell membranes and other proteins. Overall, Amylin (20-29) is an important biomolecule in understanding metabolic processes and developing therapeutic strategies for metabolic disorders.

Formula: C₄₃H₆₈N₁₂O₁₆

Synonyms:

• H-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-OH

Amylin (20-29) (human)

CAS: 118068-30-7

Amylin (20-29) (or hIAPP 20-29) forms fibrils that are ultrastructurally identical to amyloid fibrils seen in pancreatic islets. The region SNNFGAILSS appears to be the most important amyloidogenic sequence of hIAPP (human islet amyloid polypeptide).

Formula: C₄₃H₆₈N₁₂O₁₆

Purity: > 96%

Color and Shape: White Powder

Molecular weight: 1009.08

Ref: 01-4030350

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino ]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]

CAS: 118068-30-7

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₄₃H₆₈N₁₂O₁₆

Molecular weight: 1,009.09 g/mol

Ref: 3D-PP50453

Amylin (20-29) (human)

CAS: 118068-30-7

Amylin is a peptide hormone that belongs to the group of hormones that include insulin and glucagon. Amylin has been shown to have an anti-diabetic effect in diabetic patients by stimulating insulin secretion and improving insulin sensitivity. Amylin inhibits protein aggregation, which may be due to its ability to form hydrogen bonds with other amyloid protein molecules. The structural biology of amylin has been studied using NMR spectroscopy and silver ions. This molecule has a sequence of H-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser, with a molecular weight of 3,726 Da.

Formula: C₄₃H₆₈N₁₂O₁₆

Purity: Min. 95%

Molecular weight: 1,009.07 g/mol

Ref: 3D-FA109084