CAS 118120-51-7

Ofloxacin hydrochloride

Description:

Ofloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, including those affecting the respiratory tract, urinary tract, and skin. The substance is a white to pale yellow crystalline powder that is soluble in water and exhibits a pH range that is typically slightly acidic. Its molecular structure includes a bicyclic core that is essential for its mechanism of action, which involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair. Ofloxacin hydrochloride is often administered orally or intravenously, and its pharmacokinetics allow for good tissue penetration. Common side effects may include gastrointestinal disturbances, central nervous system effects, and potential tendon damage. As with other antibiotics, it is crucial to use ofloxacin hydrochloride judiciously to prevent the development of antibiotic resistance.

Formula: C₁₈H₂₀FN₃O₄·xClH

InChI: InChI=1S/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H

InChI key: InChIKey=CAOOISJXWZMLBN-UHFFFAOYSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OCC(C)N3C=C1C(O)=O.Cl

Synonyms:

• (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:?)
• 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride (1:1)
• Ofloxacin HCL
• Ofloxacinhydrochloride(R,S)(+),
• Ofloxacin hydrochloride

Ofloxacin Hydrochloride

CAS: 118120-51-7

Ofloxacin Hydrochloride

Purity: 98%

Molecular weight: 397.83g/mol

Ref: 54-PC109038

Ofloxacin HCl

CAS: 118120-51-7

Ofloxacin HCl, a synthetic antibacterial fluoroquinolone, blocks bacterial DNA gyrase to stop DNA replication.

Formula: C₁₈H₂₁ClFN₃O₄

Color and Shape: Solid

Molecular weight: 397.83

Ref: TM-T71982