CAS 118121-38-3

4-acetamido-4'-maleimidylstilbene-2,2'-disulfonic acid

Description:

4-Acetamido-4'-maleimidylstilbene-2,2'-disulfonic acid, commonly referred to as AMS, is a synthetic compound characterized by its unique structure that includes a maleimide group and sulfonic acid functionalities. This compound is known for its fluorescent properties, making it useful in various biochemical applications, particularly in labeling and detecting biomolecules. The presence of the sulfonic acid groups enhances its solubility in aqueous solutions, which is advantageous for biological assays. AMS is often utilized in the study of protein interactions and dynamics due to its ability to form stable conjugates with thiol-containing compounds, such as cysteine residues in proteins. Additionally, its acetamido group contributes to its stability and reactivity under physiological conditions. Overall, AMS serves as a valuable tool in molecular biology and biochemistry, facilitating the exploration of complex biological systems through its fluorescent and reactive characteristics.

Formula: C₂₀H₁₆N₂O₉S₂

InChI: InChI=1/C20H16N2O9S2/c1-12(23)21-15-6-4-13(17(10-15)32(26,27)28)2-3-14-5-7-16(11-18(14)33(29,30)31)22-19(24)8-9-20(22)25/h2-11H,1H3,(H,21,23)(H,26,27,28)(H,29,30,31)/b3-2+

Synonyms:

• Amids-stilbene
• Benzenesulfonic acid, 5-(acetylamino)-2-(2-(4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-2-sulfophenyl)ethenyl)-
• 5-(acetylamino)-2-{(E)-2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-sulfophenyl]ethenyl}benzenesulfonic acid
• 4-Acetamido-4'-maleimidylstilbene-2,2'-disulfonic acid