CAS 1182-87-2

Peruvoside

Description:

Peruvoside, with the CAS number 1182-87-2, is a naturally occurring glycoside primarily derived from the plant species Periploca sepium, which is part of the Asclepiadaceae family. This compound is characterized by its complex structure, which includes a sugar moiety linked to a non-sugar component, contributing to its biological activity. Peruvoside has been studied for its potential pharmacological properties, including anti-inflammatory and cardioprotective effects. It is known to exhibit effects on ion transport and may influence cellular signaling pathways. The compound is typically found in a crystalline form and is soluble in polar solvents, which is common for many glycosides. Its stability and reactivity can vary depending on environmental conditions such as pH and temperature. As with many natural products, further research is ongoing to fully elucidate its mechanisms of action and potential therapeutic applications. Safety and toxicity profiles are also important considerations in the study of peruvoside, particularly in the context of its use in traditional medicine.

Formula: C₃₀H₄₄O₉

InChI: InChI=1S/C30H44O9/c1-16-24(33)26(36-3)25(34)27(38-16)39-19-6-10-29(15-31)18(13-19)4-5-22-21(29)7-9-28(2)20(8-11-30(22,28)35)17-12-23(32)37-14-17/h12,15-16,18-22,24-27,33-35H,4-11,13-14H2,1-3H3/t16-,18+,19-,20+,21-,22+,24-,25-,26+,27-,28+,29+,30-/m0/s1

InChI key: InChIKey=PMTSPAGBAFCORP-HBUONDEYSA-N

SMILES: C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@@]1(C[C@@H](O[C@H]6[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O6)CC2)[H])[H])[H]

Synonyms:

• (3beta,5beta)-3-((6-Deoxy-3-O-methyl-alpha-L -glucopyranosyl)oxy)-14-hydroxy-19-oxocard-20(22)-enolide
• (3beta,5beta,8xi,9xi)-3-[(6-deoxy-3-O-methyl-alpha-D-glycero-hexopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
• (3β,5β)-3-[(6-Deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
• 3-((6-Deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxo-card-20(22)-enolide
• 3-[(6-deoxy-3-O-methylhexopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
• Cannogenin alpha-L-thevetoside
• Cannogenin thevetoside
• Cannogenin α-<span class="text-smallcaps">L</span>-thevetoside
• Card-20(22)-enolide, 3-((6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-19-oxo-, (3-beta,5-beta)-
• Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
• Encordin
• Peruvosid
• Cannogenin α-L-thevetoside
• Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
• (3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide

Peruvoside

CAS: 1182-87-2

Formula: C₃₀H₄₄O₉

Purity: ≥ 90%

Color and Shape: Light-yellow solid

Molecular weight: 548.66

Ref: 7W-GP1108

Peruvoside

CAS: 1182-87-2

Peruvoside

Purity: ≥95%

Molecular weight: 548.67g/mol

Ref: 54-BUP21747

Peruvoside

CAS: 1182-87-2

Formula: C₃₀H₄₄O₉

Purity: 95%~99%

Molecular weight: 548.673

Ref: BP-BP4812

Peruvoside

CAS: 1182-87-2

Peruvoside is a natural cardiac glycoside that inhibits Na+/K+-ATPas; cleukemia G₂/M phase; NSCLC Src inhibitor; MAPK Wnt / β-catenin and PI3K / AKT / mTOR.

Formula: C₃₀H₄₄O₉

Color and Shape: Solid

Molecular weight: 548.67

Ref: TM-T126270

Peruvoside

Controlled Product

CAS: 1182-87-2

Applications Peruvoside is a cardiac glycoside with the same inotropic and chronotropic effects on heart function as Ouabain (O714500).
References Ballica, R., et al.: Biotech. Bioeng., 41, 1075 (1993), Chattopadhyay, S., et al.: J. Biosci. Bioeng., 93, 215 (2002), Dong, H., et al.: Enzyme Microb. Technol., 31, 116 (2002),

Formula: C₃₀H₄₄O₉

Purity: 90%

Color and Shape: Neat

Molecular weight: 548.66

Ref: TR-P227570

Peruvoside

CAS: 1182-87-2

Peruvoside is a cardiac glycoside, which is a bioactive compound derived from the plant source Nerium oleander. This compound functions by specifically inhibiting the Na+/K+-ATPase pump, a critical membrane-bound enzyme responsible for maintaining the electrochemical gradient across the cell membrane. By disrupting the function of this pump, peruvoside leads to an increase in intracellular sodium concentration, which indirectly affects calcium ions via the sodium-calcium exchanger mechanism. This results in enhanced cardiac contractility, making peruvoside useful for certain therapeutic applications.

Formula: C₃₀H₄₄O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 548.66 g/mol

Ref: 3D-FD146105

Peruvoside-d3

Controlled Product

CAS: 1182-87-2

Formula: C₃₀D₃H₄₁O₉

Color and Shape: Neat

Molecular weight: 551.683

Ref: TR-P227572