CAS 118244-44-3

(11β)-11,17-Dihydroxy-21-[[(2E,6E)-3,7,11-trimethyl-1-oxo-2,6,10-dodecatrien-1-yl]oxy]pregna-1,4-diene-3,20-dione

Description:

The chemical substance known as (11β)-11,17-Dihydroxy-21-[[(2E,6E)-3,7,11-trimethyl-1-oxo-2,6,10-dodecatrien-1-yl]oxy]pregna-1,4-diene-3,20-dione, with the CAS number 118244-44-3, is a synthetic derivative of steroid hormones. It features a complex structure characterized by multiple hydroxyl groups and a dodecatriene side chain, which contribute to its biological activity. This compound is primarily recognized for its potential use in pharmacology, particularly in the context of anti-inflammatory and immunosuppressive therapies. The presence of the hydroxyl groups enhances its solubility and reactivity, while the steroid backbone is essential for its interaction with steroid receptors. Its unique structural features may also influence its pharmacokinetics, including absorption, distribution, metabolism, and excretion. As a synthetic compound, it may be studied for its therapeutic applications, side effects, and mechanisms of action in various biological systems. Overall, this substance exemplifies the intricate relationship between chemical structure and biological function in medicinal chemistry.

Formula: C₃₆H₅₀O₆

InChI: InChI=1S/C36H50O6/c1-23(2)9-7-10-24(3)11-8-12-25(4)19-32(40)42-22-31(39)36(41)18-16-29-28-14-13-26-20-27(37)15-17-34(26,5)33(28)30(38)21-35(29,36)6/h9,11,15,17,19-20,28-30,33,38,41H,7-8,10,12-14,16,18,21-22H2,1-6H3/b24-11+,25-19+/t28-,29-,30-,33+,34-,35-,36-/m0/s1

InChI key: InChIKey=SBQAKZYUNWNIRL-WIPKXTQKSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)=O)=O)O)[H]

Synonyms:

• (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoate
• (11β)-11,17-Dihydroxy-21-[[(2E,6E)-3,7,11-trimethyl-1-oxo-2,6,10-dodecatrien-1-yl]oxy]pregna-1,4-diene-3,20-dione
• Ccris 6595
• Pnf 21
• Prednisolone 21-all-trans-farnesylate
• Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-((3,7,11-trimethyl-1-oxo-2,6,10-dodecatrienyl)-oxy)-, (11beta,21(2E,6E))-
• Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-[(3,7,11-trimethyl-1-oxo-2,6,10-dodecatrienyl)oxy]-, [11β,21(2E,6E)]-
• Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-[[(2E,6E)-3,7,11-trimethyl-1-oxo-2,6,10-dodecatrien-1-yl]oxy]-, (11β)-
• Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-[[(2E,6E)-3,7,11-trimethyl-1-oxo-2,6,10-dodecatrienyl]oxy]-, (11β)-
• Prednisolone farnesylate

Prednisolone farnesylate

CAS: 118244-44-3

Prednisolone farnesylate is a novel transdermal corticosteroid with anti-inflammatory activity.

Formula: C₃₆H₅₀O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 578.78

Ref: TM-T12507

Prednisolone farnesylate

CAS: 118244-44-3

Prednisolone farnesylate is a synthetic, non-steroidal anti-inflammatory drug. It inhibits the inflammatory response by blocking the production of prostaglandins and leukotrienes. Prednisolone farnesylate also has been shown to activate protein ligands and inhibit protein interactions, making it a useful research tool for studying protein functions.

Formula: C₃₆H₅₀O₆

Purity: Min. 95%

Molecular weight: 578.8 g/mol

Ref: 3D-TEA24444