CAS 118253-05-7

Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT

Description:

Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT, with the CAS number 118253-05-7, is a chemical compound that belongs to the class of organic compounds known as ketones and esters. This substance features a complex structure that includes a phenylalanine (PHE) and lysine (LYS) moiety, indicating its potential role in biochemical applications, particularly in peptide synthesis or as a building block in medicinal chemistry. The presence of the 2,4,6-trimethylbenzoate group suggests it may exhibit unique physical and chemical properties, such as enhanced lipophilicity and stability. The trifluoroacetate salt form indicates that it may have improved solubility in polar solvents, which is beneficial for various applications in organic synthesis and pharmaceutical formulations. Additionally, the trifluoroacetate moiety can influence the compound's reactivity and interaction with biological systems. Overall, this compound's characteristics make it a subject of interest in research and development within the fields of organic chemistry and drug design.

Formula: C₃₄H₄₂ClN₃O₆

Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt

CAS: 118253-05-7

Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt is a proteolytic enzyme that has been shown to have bone resorption and tissue destructive properties. It is active against porphyromonas and bactericidal against fibrinogen. Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt also inhibits the formation of osteoclasts by inhibiting the uptake and protease activity of extracellular matrix proteins such as fibrinogen. This drug is currently being researched for possible use in the treatment of Alzheimer's Disease.

Formula: C₃₄H₄₁N₃O₆

Purity: Min. 95%

Molecular weight: 587.71 g/mol

Ref: 3D-FP111047

Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone

CAS: 118253-05-7

Z-FK-ck is a very effective in vivo cathepsin B inhibitor in rats. It inhibited rat liver cathepsin B activity ex vivo with ED₅₀ = 5 mg/kg intraperitoneally and 18 mg/kg orally at 4-5 h postdose, and 2.4 mg/kg subcutaneously at 24 h postdose. It also inhibited rat cathepsin B activity in heart and skeletal muscle with ED₅₀ = 0.1 and 1.0 mg/kg subcutaneously at 20 h postdose. Z-FK-ck is an inhibitor of gingipain K.

Formula: C₃₄H₄₁N₃O₆

Purity: 92.4%

Color and Shape: White

Molecular weight: 587.72

Ref: 01-4025803