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CAS 118288-08-7

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Lafutidine

Description:
Lafutidine is a synthetic compound primarily used as a medication for the treatment of gastrointestinal disorders, particularly for its role as an anti-ulcer agent. It belongs to the class of drugs known as histamine H2 receptor antagonists, which function by inhibiting the action of histamine on H2 receptors in the stomach lining, thereby reducing gastric acid secretion. This mechanism helps in alleviating conditions such as peptic ulcers and gastroesophageal reflux disease (GERD). Lafutidine is characterized by its ability to promote mucosal defense mechanisms, enhancing the production of mucus and bicarbonate, which further protects the gastric lining. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other H2 antagonists. Its pharmacokinetics involve absorption in the gastrointestinal tract, with metabolism primarily occurring in the liver. Overall, Lafutidine represents a valuable therapeutic option in managing acid-related gastrointestinal conditions, contributing to both symptom relief and mucosal healing.
Formula:C22H29N3O4S
InChI:InChI=1/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChI key:InChIKey=KMZQAVXSMUKBPD-DJWKRKHSNA-N
SMILES:C(C=1C=C(OC/C=C\CNC(CS(CC2=CC=CO2)=O)=O)N=CC1)N3CCCCC3
Synonyms:
  • (+)-2-(Furfurylsulfinyl)-N-[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]acetamide
  • (+)-2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide
  • 2-[(furan-2-ylmethyl)sulfinyl]-N-[(2Z)-4-{[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxy}but-2-en-1-yl]acetamide
  • Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-, (+)-
  • Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-, (+)-
  • Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-, (Z)-(+)-
  • Frg 8813
  • Laflutidine
  • Lafukem
  • N-(4-(4-Piperidinylmethyl)Pyridyl-2-Oxy)Butenyl-2-(Furfurylsulfinyl)Acetamide
  • See more synonyms
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Found 11 products.