CAS 118292-36-7

Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate

Description:

Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate, with CAS number 118292-36-7, is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as hydroxyl, carbonyl, and ester moieties. This compound features a hexahydro dipyrrole framework, indicating a saturated cyclic structure, and incorporates a chloromethyl group, which suggests potential reactivity and applications in further chemical synthesis. The presence of trimethoxyindole suggests biological activity, possibly related to medicinal chemistry, as indole derivatives are often associated with various pharmacological properties. The stereochemistry indicated by the (2R,8S) configuration highlights the compound's chiral nature, which can influence its biological interactions and efficacy. Overall, this compound's unique structural features and functional groups may contribute to its potential applications in pharmaceuticals or as a research chemical in organic synthesis.

Formula: C₂₆H₂₆ClN₃O₈

InChI: InChI=1S/C26H26ClN3O8/c1-26(25(34)38-5)23(32)18-17-12(9-27)10-30(14(17)8-15(31)20(18)29-26)24(33)13-6-11-7-16(35-2)21(36-3)22(37-4)19(11)28-13/h6-8,12,28-29,31H,9-10H2,1-5H3/t12-,26-/m1/s1

InChI key: InChIKey=BOGFADYROAVVTF-MZHQLVBMSA-N

SMILES: C(Cl)[C@H]1C=2C3=C(N[C@](C(OC)=O)(C)C3=O)C(O)=CC2N(C(=O)C=4NC=5C(C4)=CC(OC)=C(OC)C5OC)C1

Synonyms:

• (+)-Duocarmycin C₂
• Antibiotic SF 2582A
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R,8S)-
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R-trans)-
• Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate
• Pyrindamycin
• Sf 2582A
• methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate
• pyrindamycin A
• Duocarmycin C2

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.

Formula: C₂₆H₂₆ClN₃O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 543.95

Ref: TM-T12590

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is a natural product that is the product of a fermentation process. It has been shown to have cytotoxic properties and can be used as a chemotherapeutic agent for leukemia and other cancers. Pyrindamycin A is also an antibacterial, with activity against gram-positive and gram-negative bacteria. The mechanism of action involves steric interactions with the target tissue, leading to morphological changes in the bacterial cell wall by inhibiting the synthesis of peptidoglycan. Pyrindamycin A has been shown to inhibit leukemia inhibitory factor (LIF) production in mouse bone marrow cells, which may be due to its ability to bind to DNA. This molecule also has biological properties that are similar to those of monoclonal antibodies, including binding and inhibition of protein synthesis in sensitive cells.

Formula: C₂₆H₂₆ClN₃O₈

Purity: Min. 95%

Molecular weight: 544 g/mol

Ref: 3D-TEA29236