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CAS 118292-40-3

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Tazarotene

Description:
Tazarotene is a synthetic retinoid, primarily used in dermatology for the treatment of acne and psoriasis. It functions as a topical agent, promoting cell turnover and reducing inflammation by modulating gene expression through its action on retinoic acid receptors. Tazarotene is characterized by its ability to bind selectively to RAR (retinoic acid receptors) and RXR (retinoid X receptors), influencing skin cell differentiation and proliferation. The compound is typically formulated as a cream or gel and is applied directly to the affected areas. Its chemical structure includes a bicyclic ring system, which is essential for its biological activity. Tazarotene is known for its potential side effects, including skin irritation, dryness, and photosensitivity, necessitating careful patient management and education regarding sun protection. As a member of the retinoid family, it shares some properties with other retinoids but is distinguished by its unique efficacy and safety profile in treating specific dermatological conditions.
Formula:C21H21NO2S
InChI:InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3
InChI key:InChIKey=OGQICQVSFDPSEI-UHFFFAOYSA-N
SMILES:CC1(C)C=2C(=CC=C(C#CC3=CC=C(C(OCC)=O)C=N3)C2)SCC1
Synonyms:
  • AGN 190168
  • 3-Pyridinecarboxylic acid, 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester
  • 2H-1-Benzothiopyran, 3-pyridinecarboxylic acid deriv.
  • Tazarotene
  • 3-Pyridinecarboxylic acid, 6-[2-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester
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Found 13 products.
  • Tazarotene

    CAS:
    Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi
    Formula:C21H21NO2S
    Color and Shape:White Yellow Crystalline Powder
    Molecular weight:351.1293
  • ethyl 6-[2-(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]pyridine-3-carboxylate

    CAS:
    Formula:C21H21NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.4619

    Ref: IN-DA0076TT

    1g
    527.00€
    5g
    To inquire
    10g
    To inquire
    25g
    To inquire
    10mg
    68.00€
    50mg
    118.00€
    100mg
    159.00€
    250mg
    170.00€
  • Tazarotene

    CAS:
    Tazarotene
    Purity:99%
    Molecular weight:351.46g/mol

    Ref: 54-OR1025602

    1g
    385.00€
    5g
    1,201.00€
    100mg
    116.00€
    250mg
    174.00€
  • Tazarotene

    CAS:
    Tazarotene
    Purity:≥95%
    Molecular weight:351.46g/mol

    Ref: 54-BUP15533

    5mg
    51.00€
    10mg
    72.00€
    25mg
    124.00€
    50mg
    215.00€
    100mg
    366.00€
    200mg
    475.00€
  • Tazarotene

    CAS:
    Formula:C21H21NO2S
    Color and Shape:Pale Yellow Solid
    Molecular weight:351.46

    Ref: 4Z-T-761

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Tazarotene

    CAS:
    Formula:C21H21NO2S
    Molecular weight:351.46

    Ref: 7W-GP0240

    ne
    To inquire
  • Tazarotene

    CAS:
    Formula:C21H21NO2S
    Purity:>98.0%(GC)
    Color and Shape:White to Yellow to Green powder to crystal
    Molecular weight:351.46

    Ref: 3B-T3108

    10mg
    37.00€
    100mg
    198.00€
  • Tazarotene

    CAS:
    <p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>
    Formula:C21H21NO2S
    Purity:97.01% - 99.14%
    Color and Shape:White Solid
    Molecular weight:351.46
  • Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate

    CAS:
    Purity:95.0%
    Molecular weight:351.4599914550781

    Ref: 10-F093378

    100mg
    To inquire
    250mg
    To inquire
  • Tazarotene

    CAS:
    <p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>
    Formula:C21H21NO2S
    Color and Shape:Light Yellow
    Molecular weight:351.46

    Ref: TR-T010050

    10mg
    128.00€
    50mg
    467.00€
    250mg
    1,503.00€
  • Tazarotene

    CAS:
    <p>Binds retinoid acid receptors-γ and -β; topical treatment for skin disorders</p>
    Formula:C21H21NO2S
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:351.46 g/mol

    Ref: 3D-FT28011

    1g
    262.00€
    2g
    410.00€
    250mg
    135.00€
    500mg
    170.00€
  • Tazarotene - Bio-X ™

    CAS:
    <p>Tazarotene is an acetylenic retinoid that is used for the treatment of wrinkles, pigmentation of the skin and acne. Although, the mechanism of action for this drug is not yet fully understood, it is thought to bind to all three members of the retinoic acid receptor family. Studies have shown that this drug is associated with increased collagen production.</p>
    Formula:C21H21NO2S
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:351.46 g/mol

    Ref: 3D-BT164442

    10mg
    178.00€
  • Tazarotene

    Controlled Product
    CAS:
    Formula:C21H21NO2S
    Color and Shape:Neat
    Molecular weight:351.46

    Ref: 04-C17138900

    10mg
    Discontinued
    Discontinued product