CAS 118375-00-1

(3'aS,4'R,5'R,6'aR)-Hexahydro-5'-hydroxy-5,5-dimethyl-spiro[1,3-dioxane-2,2'(1'H)-pentalene]-4'-carboxylic Acid Methyl Ester

Controlled Product

CAS: 118375-00-1

Applications (3'aS,4'R,5'R,6'aR)-Hexahydro-5'-hydroxy-5,5-dimethyl-spiro[1,3-dioxane-2,2'(1'H)-pentalene]-4'-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud's phenomenon and ischemia.
References Sheddan, N. A., et al.: Org. Lett., 7, 5115 (2005);

Formula: C₁₅H₂₄O₅

Color and Shape: Neat

Molecular weight: 284.35

Ref: TR-H294680