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CAS 118378-76-0

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fluorescein diacetate 5-isothiocyanate

Description:
Fluorescein diacetate 5-isothiocyanate (FDI) is a fluorescent dye commonly used in biological and biochemical applications, particularly for labeling and tracking proteins and cells. It is characterized by its bright green fluorescence, which is activated upon hydrolysis in the presence of cellular esterases, making it useful for live-cell imaging. The compound features a fluorescein backbone, which contributes to its fluorescence properties, and an isothiocyanate group that facilitates covalent bonding to amino groups in proteins, allowing for specific labeling. FDI is typically soluble in organic solvents and exhibits stability under a range of conditions, although it should be protected from light to prevent photodegradation. Its ability to penetrate cell membranes and label live cells makes it a valuable tool in various research fields, including cell biology, molecular biology, and biochemistry. Safety precautions should be taken when handling this compound, as isothiocyanates can be reactive and potentially hazardous.
Formula:C25H15NO7S
Synonyms:
  • Fluorescein-5-Isothiocyanate Diacetate
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Found 3 products.
  • 5-FITC DA
    Glentham
    + Info

    5-FITC DA

    CAS:

    Ref: 7W-GW8985

    50mg
    339.00€
    250mg
    1,128.00€
  • Fluorescein-diacetate-5-isothiocyanate
    TRC
    + Info

    Fluorescein-diacetate-5-isothiocyanate

    Controlled Product
    CAS:
    <p>Applications Fluorescein-diacetate-5-isothiocyanate is a useful intermediate in the preparation of fluorogenic aldol substrates for aldolase antibody 38C2.<br>References List, B., et al.: Proc. Natl. Acad. Sci. USA, 95, 15351 (1998)<br></p>
    Formula:C25H15NO7S
    Color and Shape:Neat
    Molecular weight:473.454

    Ref: TR-F537560

    250mg
    1,022.00€
  • Fluorescein diacetate 5-isothiocyanate
    Biosynth
    + Info

    Fluorescein diacetate 5-isothiocyanate

    CAS:
    <p>Fluorescein diacetate 5-isothiocyanate (FDIA) is a prodrug that is metabolized by esterases to an active form, fluorescein 5-isothiocyanate. FDIA has been shown to be a potent photosensitizer that can be used for the treatment of cancerous tumors in human skin. It binds to the tumor cells and then is activated by light of a certain wavelength. This activation leads to cellular death. The photosensitizer FDIA has been shown to have a persistent effect on the skin with only one dose and its metabolism rate is high enough that it can be used therapeutically in neonatal patients.</p>
    Formula:C25H15NO7S
    Purity:Min. 95%
    Molecular weight:473.05692

    Ref: 3D-FF04412

    100mg
    863.00€