CAS 118395-73-6: Chloroeremomycin
Description:Chloroeremomycin is a chemical compound classified as a macrolide antibiotic, derived from the fermentation of certain actinomycetes. It is known for its antibacterial properties, particularly against Gram-positive bacteria. The structure of chloroeremomycin features a large lactone ring, which is characteristic of macrolides, and it contains chlorine substituents that contribute to its biological activity. This compound exhibits a mechanism of action similar to other macrolides, primarily by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit. Chloroeremomycin has been studied for its potential therapeutic applications, especially in treating infections caused by resistant bacterial strains. Its pharmacological profile includes considerations of solubility, stability, and bioavailability, which are crucial for its effectiveness as an antibiotic. Additionally, like many antibiotics, it may have side effects and resistance patterns that are important for clinical use. Overall, chloroeremomycin represents a significant compound in the field of medicinal chemistry and antibiotic development.
Formula:C73H88Cl2N10O26
InChI:InChI=1S/C73H88Cl2N10O26/c1-26(2)14-38(79-7)64(96)84-54-56(91)30-9-12-42(36(74)16-30)106-44-18-32-19-45(60(44)111-71-61(58(93)57(92)46(25-86)108-71)110-49-24-73(6,78)63(95)28(4)105-49)107-43-13-10-31(17-37(43)75)59(109-48-23-72(5,77)62(94)27(3)104-48)55-69(101)83-53(70(102)103)35-20-33(87)21-41(89)50(35)34-15-29(8-11-40(34)88)51(66(98)85-55)82-67(99)52(32)81-65(97)39(22-47(76)90)80-68(54)100/h8-13,15-21,26-28,38-39,46,48-49,51-59,61-63,71,79,86-89,91-95H,14,22-25,77-78H2,1-7H3,(H2,76,90)(H,80,100)(H,81,97)(H,82,99)(H,83,101)(H,84,96)(H,85,98)(H,102,103)/t27-,28-,38+,39-,46+,48-,49-,51+,52+,53-,54+,55-,56+,57+,58-,59+,61+,62-,63-,71-,72-,73-/m0/s1
InChI key:InChIKey=XJHXLMVKYIVZTE-LOALFDMRSA-N
SMILES:O=C(O)C1NC(=O)C2NC(=O)C(NC(=O)C3NC(=O)C(NC(=O)C(NC(=O)C(NC)CC(C)C)C(O)C4=CC=C(OC=5C=C3C=C(OC6=CC=C(C=C6Cl)C2OC7OC(C)C(O)C(N)(C)C7)C5OC8OC(CO)C(O)C(O)C8OC9OC(C)C(O)C(N)(C)C9)C(Cl)=C4)CC(=O)N)C%10=CC=C(O)C(=C%10)C%11=C(O)C=C(O)C=C%111
- Synonyms:
- (1S,2R,18R,19R,22S,25R,28R,40R)-2-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-48-{[(2S,3R,5S,6R)-3-{[(2S,4S,5R,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-18,32,35,37-tetrahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
- (4′′R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)vancomycin
- 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
- 8-82846A
- A 82846B
- A83846B
- Antibiotic A 82846B
- Antibiotic PA 45052A
- Chloroeremomycin
- Ly 264826
- See more synonyms
- Pa 45052A
- Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-, (4''R)-
- Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)-, (4′′R)-
- (4′′R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)vancomycin
- A82846
- Chloroorienticin A
- Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-, (4′′R)-
Brand | Product data | Purity | Price range | Estimated delivery |
---|---|---|---|---|
![]() | Chloroorienticin A REF: TM-T27008CAS: 118395-73-6 | 98% | To inquire | Tue 04 Mar 25 |
![]() | Chloroorienticin A REF: 4Z-O-093001CAS: 118395-73-6 | - - - | To inquire | Tue 04 Mar 25 |
![]() | Chloroeremomycin REF: 3D-AC167119CAS: 118395-73-6 | Min. 95% | 147.00 €~2,385.00 € | Fri 14 Mar 25 |
![discount label](https://static.cymitquimica.com/public/img/discount.png)
Chloroorienticin A
Ref: TM-T27008
100mg | To inquire | ||
500mg | To inquire |
![discount label](https://static.cymitquimica.com/public/img/discount.png)
Ref: 4Z-O-093001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
![discount label](https://static.cymitquimica.com/public/img/discount.png)
Chloroeremomycin
Ref: 3D-AC167119
50mg | 147.00 € | ||
100mg | 219.00 € |