CAS 118409-57-7: tyrphostin 23

Description: Tyrphostin 23, with the CAS number 118409-57-7, is a synthetic compound known for its role as a selective inhibitor of receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR). This compound is part of a broader class of tyrphostins, which are characterized by their ability to interfere with signal transduction pathways involved in cell growth and differentiation. Tyrphostin 23 has been studied for its potential therapeutic applications in cancer treatment, as it can inhibit tumor cell proliferation and induce apoptosis in certain cancer cell lines. The compound typically exhibits moderate solubility in organic solvents and is often used in biochemical research to elucidate the mechanisms of receptor signaling. Its structure includes specific functional groups that contribute to its inhibitory activity, making it a valuable tool in pharmacological studies. As with many chemical substances, handling and usage should adhere to safety protocols to mitigate any potential hazards associated with its biological activity.

Formula: C₁₀H₆N₂O₂

InChI: InChI=1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H

InChI key: InChIKey=VTJXFTPMFYAJJU-UHFFFAOYSA-N

SMILES: N#CC(C#N)=CC1=CC=C(O)C(O)=C1

Synonyms:

• (3,4-Dihydroxybenzylidene)malononitrile
• 2-(3,4-Dihydroxybenzylidene)malononitrile
• 2-[(3,4-Dihydroxyphenyl)methylene]propanedinitrile
• 2-[(3,4-Dihydroxyphenyl)methylidene]propanedinitrile
• AG 18 (pharmaceutical)
• Ag 18
• Propanedinitrile, 2-[(3,4-dihydroxyphenyl)methylene]-
• Propanedinitrile, [(3,4-dihydroxyphenyl)methylene]-
• Rg 50810
• Rg 50858
• Tx 825
• Tyrphostin A 23
• Tyrphostin AG 18

Tyrphostin A23

CAS: 118409-57-7

• Formula: C₁₀H₆N₂O₂
• Purity: >98.0%(GC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 186.17

Tyrphostin A23, 99%

CAS: 118409-57-7

Tyrphostin inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors …

• Formula: C₁₀H₆N₂O₂
• Purity: 99%
• Molecular weight: 186.17

Tyrphostin 23

CAS: 118409-57-7

• Formula: C₁₀H₆N₂O₂
• Purity: (GC) ≥ 98.0%
• Color and Shape: White to light yellow crystalline powder
• Molecular weight: 186.17

2-(3,4-Dihydroxybenzylidene)Malononitrile

CAS: 118409-57-7

• Purity: 0.98
• Molecular weight: 186.17g/mol

Tyrphostin 23

CAS: 118409-57-7

Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.

• Formula: C₁₀H₆N₂O₂
• Purity: 99.19% - 99.7%
• Color and Shape: Yellow-Tan Solid
• Molecular weight: 186.17

Tyrphostin 23

CAS: 118409-57-7

Stability Store in refrigerator Applications A specific inhibitor for the epidermal growth factor receptor. Also …

• Formula: C₁₀H₆N₂O₂
• Color and Shape: Neat
• Molecular weight: 186.17

Tyrphostin 23

CAS: 118409-57-7

Please enquire for more information about Tyrphostin 23 including the price, delivery time and more …

• Formula: C₁₀H₆N₂O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 186.17 g/mol