CAS 118409-58-8

tyrphostin 25

Description:

Tyrphostin 25, with the CAS number 118409-58-8, is a synthetic compound that belongs to a class of molecules known as tyrosine kinase inhibitors. It is primarily recognized for its role in research related to cancer and cellular signaling pathways. Tyrphostin 25 exhibits the ability to inhibit specific receptor tyrosine kinases, which are crucial in regulating various cellular processes, including proliferation, differentiation, and survival. This compound has been studied for its potential therapeutic applications, particularly in the context of tumor growth and metastasis. In addition to its anti-cancer properties, tyrphostin 25 may also influence other biological processes, making it a valuable tool in pharmacological research. Its chemical structure typically includes functional groups that facilitate its interaction with target proteins, contributing to its inhibitory effects. As with many research chemicals, safety and handling precautions are essential, as the compound may pose risks if not managed properly in laboratory settings.

Formula: C₁₀H₆N₂O₃

InChI: InChI=1/C10H6N2O3/c11-4-7(5-12)1-6-2-8(13)10(15)9(14)3-6/h1-3,13-15H

SMILES: C(=C(C#N)C#N)c1cc(c(c(c1)O)O)O

Synonyms:

• Ag 82
• (3,4,5-Trihydroxybenzylidene)Propanedinitrile

Propanedinitrile, 2-[(3,4,5-trihydroxyphenyl)methylene]-

CAS: 118409-58-8

Formula: C₁₀H₆N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 202.16624

Ref: IN-DA001NLO

Tyrphostin A25

CAS: 118409-58-8

Tyrphostin A25

Purity: ≥98%

Molecular weight: 202.17g/mol

Ref: 54-BUP02128

Tyrphostin 25

Controlled Product

CAS: 118409-58-8

Stability Hygroscopic, Light Sensitive
Applications An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 µM for the autophosphorylation of the EGF-receptor.
References Gazit, A., et al.: J. Med. Chem., 32, 2344 (1989)

Formula: C₁₀H₆N₂O₃

Color and Shape: Neat

Molecular weight: 202.17

Ref: TR-T925000

Tyrphostin A25

CAS: 118409-58-8

Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.

Formula: C₁₀H₆N₂O₃

Purity: 98.98%

Color and Shape: Yellow Green Powder /Off-White Solid

Molecular weight: 202.17

Ref: TM-T21622