CAS 1184173-73-6

MK-8353

CAS: 1184173-73-6

Formula: C₃₇H₄₁N₉O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 691.8449

Ref: IN-DA01FVJ9

MK-8353

CAS: 1184173-73-6

MK-8353

Purity: ≥95%

Molecular weight: 691.84g/mol

Ref: 54-BUP14183

MK-8353 (SCH900353)

CAS: 1184173-73-6

MK-8353 is a novel, potent and selective inhibitor of the mek1/2 enzyme. It is active in vitro against a variety of human cancer cell lines, including metastatic colorectal cancer cells that are resistant to other tyrosine kinase inhibitors. MK-8353 has been found to inhibit tumor growth in vivo by inhibiting the phosphorylation of mek1/2 and its downstream signaling pathways. The compound also inhibited mutant melanoma growth in vivo and suppressed the proliferation of cervical cancer cells in vitro. MK-8353 is currently being evaluated for use as a potential anticancer drug candidate.

Formula: C₃₇H₄₁N₉O₃S

Purity: Min. 95%

Molecular weight: 691.84 g/mol

Ref: 3D-JXB17373

MK-8353

CAS: 1184173-73-6

MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)

Formula: C₃₇H₄₁N₉O₃S

Purity: 96.15% - 97.19%

Color and Shape: Solid

Molecular weight: 691.84

Ref: TM-T12069